Mental illness represents a major health issue both at the individual and at the
socioeconomical level. This is partly due to the current suboptimal treatment options …

Clozapine is an efficacious atypical antipsychotic for treatment-refractory schizophrenia.
Clinical response and appearance of adverse events vary among individual patients …

Biomarkers which predict response to atypical antipsychotic drugs (AAPDs) increases their
benefit/risk ratio. We sought to identify common variants in genes which predict response to …

Background Emotion recognition skills are essential for social communication. Deficits in
these skills have been implicated in mental disorders. Prior studies of clinical and high‐risk …

In this article, the current literature on pharmacogenetics of antidepressants, antipsychotics
and lithium are summarized by the section of Neurobiology and Genetics of the German …

Methods of estimating the local false discovery rate (LFDR) have been applied to different
types of datasets such as high-throughput biological data, diffusion tensor imaging (DTI) …

Disclosed are methods and kits for diagnosing, prognosing, and treating patients having
psychiatric disorders. The methods may include assessing whether a patient has a treatment …

Atypical antipsychotics are commonly prescribed for the treatment of psychiatric disorders
such as schizophrenia. However, long term use of atypical antipsychotics lead to metabolic …

Psychopharmaka sind ein wichtiger Baustein in der Behandlung einer Vielzahl
psychiatrischer Erkrankungen. Die Therapie wird jedoch häufig durch unzureichendes …

Abstract (DE) Eine Vielzahl von Krankheiten und Phänotypen im Menschen werden durch
Mutationen in G-Protein-gekoppelten Rezeptoren (GPCR) verursacht. Die Klasse der …