Summary T helper 17 (Th17) cells play critical roles in inflammatory and autoimmune
diseases. The lineage‐specific transcription factor ROR γt is the key regulator for Th17 cell …

Recent studies have shown that on one hand, tumors need to obtain a sufficient energy
supply, and on the other hand they must evade the body's immune surveillance. Because of …

Sepsis has always been considered as a big challenge for pharmaceutical companies in
terms of discovering and designing new therapeutics. The pathogenesis of sepsis involves …

Background: Fibroblast proliferation is a critical feature during heart failure development.
Previous studies reported regulatory T-lymphocytes (Tregs)'protective role against …

Biogenic amines are direct mediators of interactions between immune and nervous systems
implicated in the pathogenesis of multiple sclerosis (MS). Recently, great attention has been …

Recent studies have revealed a relationship between cellular metabolism and cell function
in immune cells. Cellular metabolism not only provides supplemental ATP, but also supports …

Background: T helper 17 (Th17) cells and regulatory T cells (Tregs) are derived from naive
CD4+ T cells. It remains contentious as to whether the balance between Th17 and Tregs is …

The T helper 17 cells (Th17 cells) are a type of T cells that plays an important role in the
adaptive immune system. Studies show that Th17/regulatory T cells (Treg) imbalance, as …

Effector CD4 T cells are essential for the balance between pro-and anti-inflammatory
immune responses during homeostasis. Dysregulation of effector CD4 T cell responses …