Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history

SA Bonini, M Premoli, S Tambaro, A Kumar… - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance Cannabis sativa L.(C. sativa) is an annual dioecious plant,
which shares its origins with the inception of the first agricultural human societies in Asia …

Translational investigation of the therapeutic potential of cannabidiol (CBD): toward a new age

JA Crippa, FS Guimarães, AC Campos… - Frontiers in …, 2018 - frontiersin.org
Background: Among the many cannabinoids in the cannabis plant, cannabidiol (CBD) is a
compound that does not produce the typical subjective effects of marijuana. Objectives: The …

Medical use of cannabinoids

AI Fraguas-Sánchez, AI Torres-Suárez - Drugs, 2018 - Springer
Cannabinoid receptors, endocannabinoids and the enzymes responsible for their
biosynthesis and degradation constitute the endocannabinoid system. In recent decades …

[HTML][HTML] Review of the neurological benefits of phytocannabinoids

J Maroon, J Bost - Surgical neurology international, 2018 - ncbi.nlm.nih.gov
Background: Numerous physical, psychological, and emotional benefits have been
attributed to marijuana since its first reported use in 2,600 BC in a Chinese pharmacopoeia …

Clinical and preclinical evidence for functional interactions of cannabidiol and Δ9-tetrahydrocannabinol

DL Boggs, JD Nguyen, D Morgenson… - …, 2018 - nature.com
The plant Cannabis sativa, commonly called cannabis or marijuana, has been used for its
psychotropic and mind-altering side effects for millennia. There has been growing attention …

[HTML][HTML] Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test

IM Linares, AW Zuardi, LC Pereira… - Brazilian Journal of …, 2018 - SciELO Brasil
Objective: Cannabidiol (CBD), one of the non-psychotomimetic compounds of Cannabis
sativa, causes anxiolytic-like effects in animals, with typical bell-shaped dose-response …

[HTML][HTML] A naturalistic examination of the perceived effects of cannabis on negative affect

C Cuttler, A Spradlin, RJ McLaughlin - Journal of affective disorders, 2018 - Elsevier
Background Cannabis is commonly used to alleviate symptoms of negative affect. However,
a paucity of research has examined the acute effects of cannabis on negative affect in …

A reliable and validated LC-MS/MS method for the simultaneous quantification of 4 cannabinoids in 40 consumer products

Q Meng, B Buchanan, J Zuccolo, MM Poulin… - PLoS …, 2018 - journals.plos.org
In the past 50 years, Cannabis sativa (C. sativa) has gone from a substance essentially
prohibited worldwide to one that is gaining acceptance both culturally and legally in many …

Cannabidiol reverses attentional bias to cigarette cues in a human experimental model of tobacco withdrawal

C Hindocha, TP Freeman, M Grabski, JB Stroud… - …, 2018 - Wiley Online Library
Abstract Background and Aims Cannabidiol (CBD), a non‐intoxicating cannabinoid found in
cannabis, may be a promising novel smoking cessation treatment due to its anxiolytic …

No acute effects of cannabidiol on the sleep-wake cycle of healthy subjects: a randomized, double-blind, placebo-controlled, crossover study

IMP Linares, FS Guimaraes, A Eckeli… - Frontiers in …, 2018 - frontiersin.org
Cannabidiol (CBD) is a component of Cannabis sativa that has a broad spectrum of
potential therapeutic effects in neuropsychiatric and other disorders. However, few studies …