Redox signaling by reactive electrophiles and oxidants

S Parvez, MJC Long, JR Poganik, Y Aye - Chemical reviews, 2018 - ACS Publications
The concept of cell signaling in the context of nonenzyme-assisted protein modifications by
reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely …

On the history of oxidative stress: Concept and some aspects of current development

H Sies - Current Opinion in Toxicology, 2018 - Elsevier
Oxidative stress as a concept in redox biology and medicine has witnessed fulminant
development of the past 30-odd years. It is a global concept, defined as “an imbalance …

[HTML][HTML] Acetate production from glucose and coupling to mitochondrial metabolism in mammals

X Liu, DE Cooper, AA Cluntun, MO Warmoes, S Zhao… - Cell, 2018 - cell.com
Acetate is a major nutrient that supports acetyl-coenzyme A (Ac-CoA) metabolism and thus
lipogenesis and protein acetylation. However, its source is unclear. Here, we report that …

Free radicals and the role of plant phytochemicals as antioxidants against oxidative stress-related diseases

GA Engwa - Phytochemicals: source of antioxidants and role in …, 2018 - books.google.com
Free radicals or reactive oxygen species (ROS) generated from various sources in the
environment as well as from cellular processes in the body are of serious health challenges …

Antioxidants from plants protect against skin photoaging

G Petruk, R Del Giudice, MM Rigano… - … medicine and cellular …, 2018 - Wiley Online Library
Exposure to UV light triggers the rapid generation and accumulation of reactive oxygen
species (ROS) in skin cells, with consequent increase in oxidative stress and thus in …

Mitochondria and reactive oxygen species in aging and age-related diseases

C Giorgi, S Marchi, ICM Simoes, Z Ren… - International review of …, 2018 - Elsevier
Aging has been linked to several degenerative processes that, through the accumulation of
molecular and cellular damage, can progressively lead to cell dysfunction and organ failure …

The mechanism of cone cell death in Retinitis Pigmentosa

PA Campochiaro, TA Mir - Progress in retinal and eye research, 2018 - Elsevier
Retinitis Pigmentosa (RP) is a group of diseases in which one of a large number of
mutations causes death of rod photoreceptors. After rods die, cone photoreceptors slowly …

[HTML][HTML] Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and …

B Kalyanaraman, G Cheng, M Hardy, O Ouari… - Redox biology, 2018 - Elsevier
Reactive oxygen species (ROS) have been implicated in tumorigenesis (tumor initiation,
tumor progression, and metastasis). Of the many cellular sources of ROS generation, the …

[HTML][HTML] An antibacterial platform based on capacitive carbon-doped TiO2 nanotubes after direct or alternating current charging

G Wang, H Feng, L Hu, W Jin, Q Hao, A Gao… - Nature …, 2018 - nature.com
Electrical interactions between bacteria and the environment are delicate and essential. In
this study, an external electrical current is applied to capacitive titania nanotubes doped with …

[HTML][HTML] Mitochondrial quality control in neurodegenerative diseases: focus on Parkinson's disease and Huntington's disease

S Franco-Iborra, M Vila, C Perier - Frontiers in neuroscience, 2018 - frontiersin.org
In recent years, several important advances have been made in our understanding of the
pathways that lead to cell dysfunction and death in Parkinson's disease (PD) and …