Shox2: The role in differentiation and development of cardiac conduction system
W Hu, Y Xin, Y Zhao, J Hu - The Tohoku Journal of Experimental …, 2018 - jstage.jst.go.jp
The formation and conduction of electrocardiosignals and the synchronous contraction of
atria and ventricles with rhythmicity are both triggered and regulated by the cardiac …
atria and ventricles with rhythmicity are both triggered and regulated by the cardiac …
Induced pluripotent stem cells to study mechanisms of laminopathies: focus on epigenetics
S Crasto, E Di Pasquale - Frontiers in cell and developmental biology, 2018 - frontiersin.org
Laminopathies are a group of rare degenerative disorders that manifest with a wide
spectrum of clinical phenotypes, including both systemic multi-organ disorders, such as the …
spectrum of clinical phenotypes, including both systemic multi-organ disorders, such as the …
In vitro and in vivo differentiation of induced pluripotent stem cells generated from urine-derived cells into cardiomyocytes
YF Jiang, M Chen, NN Zhang, HJ Yang, Q Rui… - Biology …, 2018 - journals.biologists.com
Generation of human cardiomyocytes from cells derived from various sources, including skin
biopsy, has been made possible by breakthrough advances in stem cell research. However …
biopsy, has been made possible by breakthrough advances in stem cell research. However …
Implications of cellular aging in cardiac reprogramming
Aging is characterized by a chronic functional decline of organ systems which leads to tissue
dysfunction over time, representing a risk factor for diseases development, including …
dysfunction over time, representing a risk factor for diseases development, including …
Studying KCNQ1 Mutation and Drug Response in Type 1 Long QT Syndrome Using Patient-Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes
H Wei, J Wu, Z Liu - Potassium Channels: Methods and Protocols, 2018 - Springer
Patient-specific human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes
(hiPSC-CMs) are becoming a valuable model for studying inherited cardiac arrhythmias …
(hiPSC-CMs) are becoming a valuable model for studying inherited cardiac arrhythmias …
[PDF][PDF] Reprogramming of human skin fibroblasts into functional cardiomyocytes–insights into molecular pathology of CPVT disorder
P Dvořák, CSI Aćimović - is.muni.cz
Background: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a highly
lethal inherited arrhythmogenic disorder occurring in the absence of a structural heart …
lethal inherited arrhythmogenic disorder occurring in the absence of a structural heart …