Bleeding and thrombotic complications in the use of extracorporeal membrane oxygenation

J Thomas, V Kostousov, J Teruya - Seminars in thrombosis and …, 2018 - thieme-connect.com
Extracorporeal membrane oxygenation (ECMO) has been used for> 40 years to support
lung and heart failure; however, bleeding and thrombosis remain serious complications. The …

Current understanding of how extracorporeal membrane oxygenators activate haemostasis and other blood components

AJ Doyle, BJ Hunt - Frontiers in medicine, 2018 - frontiersin.org
Extracorporeal membrane oxygenators are used in critical care for the management of
severe respiratory and cardiac failure. Activation of the coagulation system is initiated by the …

Iron in the tumor microenvironment—connecting the dots

C Pfeifhofer-Obermair, P Tymoszuk, V Petzer… - Frontiers in …, 2018 - frontiersin.org
Iron metabolism and tumor biology are intimately linked. Iron facilitates the production of
oxygen radicals, which may either result in iron-induced cell death, ferroptosis, or contribute …

Intracranial hemorrhage in adults on ECMO

YA Cavayas, L Del Sorbo, E Fan - Perfusion, 2018 - journals.sagepub.com
Rationale: Extracorporeal membrane oxygenation (ECMO) use has exploded over the last
decade. However, it remains invasive and associated with significant complications …

Cerebral near-infrared spectroscopy in adult patients undergoing veno-arterial extracorporeal membrane oxygenation

S Pozzebon, A Blandino Ortiz, F Franchi, S Cristallini… - Neurocritical care, 2018 - Springer
Background Acute cerebral complications (ACC) of veno-arterial extracorporeal membrane
oxygenation (VA-ECMO) are associated with poor long-term neurologic outcome. We …

[HTML][HTML] Haemolysis index for the screening of intravascular haemolysis: a novel diagnostic opportunity?

G Lippi, EJ Favaloro, M Franchini - Blood Transfusion, 2018 - ncbi.nlm.nih.gov
The diagnostic approach to patients with intravascular haemolysis remains challenging,
since no first-line laboratory test seems to be entirely suitable for the screening of this …

von Willebrand factor, free hemoglobin and thrombosis in ECMO

C Valladolid, A Yee, MA Cruz - Frontiers in Medicine, 2018 - frontiersin.org
Though extracorporeal membrane oxygenation (ECMO) provides life-saving support, this
intervention exposes patients to certain risks. Circulating free hemoglobin (fHb) resulting …

An analysis of risk factors for hemolysis in children on extracorporeal membrane oxygenation

S Okochi, EW Cheung, S Barton… - Pediatric Critical Care …, 2018 - journals.lww.com
Objectives: Hemolysis is a known complication of pediatric extracorporeal membrane
oxygenation associated with renal failure and mortality. We sought to identify predictors of …

Oxidative stress and neonatal respiratory extracorporeal membrane oxygenation

G Raffaeli, S Ghirardello, S Passera, F Mosca… - Frontiers in …, 2018 - frontiersin.org
Oxidative stress is a frequent condition in critically ill patients, especially if exposed to
extracorporeal circulation, and it is associated with worse outcomes and increased mortality …

Impact of hemolysis on acute kidney injury and mortality in children supported with cardiac extracorporeal membrane oxygenation

S Borasino, Y Kalra, AR Elam… - The Journal of …, 2018 - ject.edpsciences.org
Intravascular hemolysis with elevated plasma-free hemoglobin (PFH) complicates
extracorporeal membrane oxygenation (ECMO). In 50 consecutive pediatric cardiac patients …