Retinoic acid and 6-formylindolo (3, 2-b) carbazole (FICZ) combination therapy reveals putative targets for enhancing response in non-APL AML
RP Bunaciu, RJ MacDonald, HA Jensen… - Leukemia & …, 2018 - Taylor & Francis
In non-acute promyelotic leukemia (APL)-non myelocytic leukemia (AML), identification of a
signaling signature would predict potentially actionable targets to enhance differentiation …
signaling signature would predict potentially actionable targets to enhance differentiation …
[HTML][HTML] The c-Raf modulator RRD-251 enhances nuclear c-Raf/GSK-3/VDR axis signaling and augments 1, 25-dihydroxyvitamin D3-induced differentiation of HL-60 …
HT Supnick, RP Bunaciu, A Yen - Oncotarget, 2018 - ncbi.nlm.nih.gov
Differentiation therapy is used in cancer treatment. Epidemiologic studies showed that
higher vitamin D levels are associated with reduced cancer risks. However, the therapeutic …
higher vitamin D levels are associated with reduced cancer risks. However, the therapeutic …
CXCR5 overexpression in HL-60 cells enhances chemotaxis toward CXCL13 without anticipated interaction partners or enhanced MAPK signaling
RJ MacDonald, A Yen - In Vitro Cellular & Developmental Biology-Animal, 2018 - Springer
CXCR5 is a serpentine receptor implicated in cell migration in lymphocytes and
differentiation in leukocytes. It causes MAPK pathway activation and has known membrane …
differentiation in leukocytes. It causes MAPK pathway activation and has known membrane …