The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as
dental caries and periodontitis, two of the most prevalent microbially induced disorders …

Objectives This review proposes case definitions and diagnostic considerations of systemic
disorders and conditions that affect the periodontal attachment apparatus. Importance …

Periodontitis is one of the most common human inflammatory diseases, yet the mechanisms
that drive immunopathology and could be therapeutically targeted are not well defined …

The oral mucosal barrier is constantly exposed to a plethora of triggers requiring immune
control, including a diverse commensal microbiome, ongoing damage from mastication, and …

A wide range of bacterial species are harbored in the oral cavity, with the resulting complex
network of interactions between the microbiome and host contributing to physiological as …

γδ T cells are enriched at barrier sites such as the gut, skin, and lung, where their roles in
maintaining barrier integrity are well established. However, how these cells contribute to …

Periodontal diseases are among the most prevalent worldwide, but largely silent, chronic
diseases. They affect the tooth-supporting tissues with multiple ramifications on life quality …

The skin and orogenital mucosae, which constitute complex protective barriers against
infection and injuries, are not only the first to come into contact with pathogens but are also …

Toll-like receptors (TLRs) are a group of pattern recognition receptors (PRRs) that provide
innate immune sensing of conserved pathogen-associated molecular patterns (PAMPs) to …

In the oral cavity, the immune system is constantly exposed to unique tissue‐specific signals,
including a rich community of commensal microbes and their metabolites, continuous tissue …