Lung cancer: active therapeutic targeting and inhalational nanoproduct design
Introduction: Pulmonary drug delivery is organ-specific and benefits local drug action for
lung cancer. The use of nanotechnology and targeting ligand enables cellular-specific drug …
lung cancer. The use of nanotechnology and targeting ligand enables cellular-specific drug …
Ultrasonically controlled estrone-modified liposomes for estrogen-positive breast cancer therapy
A new modality of drug targeting to tumors has been proposed. The ligand-mediated
approach, that already increases the therapeutic index of the drug, can still be optimized by …
approach, that already increases the therapeutic index of the drug, can still be optimized by …
[HTML][HTML] Plectin-targeted liposomes enhance the therapeutic efficacy of a PARP inhibitor in the treatment of ovarian cancer
SSK Dasa, G Diakova, R Suzuki, AM Mills… - Theranostics, 2018 - ncbi.nlm.nih.gov
Advances in genomics and proteomics drive precision medicine by providing actionable
genetic alterations and molecularly targeted therapies, respectively. While genomic analysis …
genetic alterations and molecularly targeted therapies, respectively. While genomic analysis …
Nilotinib as coadjuvant treatment with doxorubicin in patients with sarcomas: a phase I trial of the spanish group for research on sarcoma
Purpose: Nilotinib plus doxorubicin showed to be synergistic regarding apoptosis in several
sarcoma cell lines. A phase I/II trial was thus designed to explore the feasibility of nilotinib as …
sarcoma cell lines. A phase I/II trial was thus designed to explore the feasibility of nilotinib as …
Targeting the leptin receptor: To evaluate therapeutic efficacy and anti-tumor effects of Doxil, in vitro and in vivo in mice bearing C26 colon carcinoma tumor
SA Darban, S Nikoofal-Sahlabadi, N Amiri… - Colloids and Surfaces B …, 2018 - Elsevier
Leptin is an appetite regulatory hormone that is secreted into the blood circulation by the
adipose tissue and it functions via its over expressed receptors (Ob-R) in a wide variety of …
adipose tissue and it functions via its over expressed receptors (Ob-R) in a wide variety of …
Development of nanoscale oil bodies for targeted treatment of lung cancer
Lung cancer is the most widespread disease and is frequently associated with a high level
of epidermal growth factor receptor (EGFR). This study was thus conducted to provide a …
of epidermal growth factor receptor (EGFR). This study was thus conducted to provide a …
Spectral investigations and DFT studies of 3, 7-dihydro-1, 3, 7-trimethyl-1H-purine-2, 6-dione (caffeine) interaction and recognition by single amino acid derived self …
R Govindhan, B Karthikeyan - Journal of molecular structure, 2018 - Elsevier
Recognition of xanthine alkaloid caffeine with 3, 5-bis (trifluoromethyl) benzylamine derived
peptide nanotubes (BTTPNTs) through chemical interaction have been achieved through …
peptide nanotubes (BTTPNTs) through chemical interaction have been achieved through …