Current enlightenment about etiology and pharmacological treatment of autism spectrum disorder
Autistic Spectrum Disorder (ASD) is a complex neurodevelopmental brain disorder
characterized by two core behavioral symptoms, namely impairments in social …
characterized by two core behavioral symptoms, namely impairments in social …
Genetics of autism spectrum disorder
G Ramaswami, DH Geschwind - Handbook of clinical neurology, 2018 - Elsevier
Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder characterized
by impaired social interaction and stereotyped behaviors. ASD has a strong and complex …
by impaired social interaction and stereotyped behaviors. ASD has a strong and complex …
Glutamate and GABA in autism spectrum disorder—a translational magnetic resonance spectroscopy study in man and rodent models
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental syndrome with a high
human and economic burden. The pathophysiology of ASD is largely unclear, thus …
human and economic burden. The pathophysiology of ASD is largely unclear, thus …
Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition
Haploinsufficiency of the SHANK3 gene is causally linked to autism spectrum disorder
(ASD), and ASD-associated genes are also enriched for chromatin remodelers. Here we …
(ASD), and ASD-associated genes are also enriched for chromatin remodelers. Here we …
Prenatal fever and autism risk
M Hornig, MA Bresnahan, X Che, AF Schultz… - Molecular …, 2018 - nature.com
Some studies suggest that prenatal infection increases risk of autism spectrum disorders
(ASDs). This study was undertaken in a prospective cohort in Norway to examine whether …
(ASDs). This study was undertaken in a prospective cohort in Norway to examine whether …
Genome-wide meta-analysis of cognitive empathy: heritability, and correlates with sex, neuropsychiatric conditions and cognition
We conducted a genome-wide meta-analysis of cognitive empathy using the 'Reading the
Mind in the Eyes' Test (Eyes Test) in 88,056 research volunteers of European Ancestry …
Mind in the Eyes' Test (Eyes Test) in 88,056 research volunteers of European Ancestry …
Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing
Common genetic contributions to autism spectrum disorder (ASD) reside in risk gene
variants that individually have minimal effect sizes. As environmental factors that perturb …
variants that individually have minimal effect sizes. As environmental factors that perturb …
A population genetic interpretation of GWAS findings for human quantitative traits
Human genome-wide association studies (GWASs) are revealing the genetic architecture of
anthropomorphic and biomedical traits, ie, the frequencies and effect sizes of variants that …
anthropomorphic and biomedical traits, ie, the frequencies and effect sizes of variants that …
Neural circuits for social cognition: implications for autism
M Fernández, I Mollinedo-Gajate, O Peñagarikano - Neuroscience, 2018 - Elsevier
Social neuroscience, the study of the neurobiological basis of social behavior, has become
a major area of current research in behavioral neuroscience and psychiatry, since many …
a major area of current research in behavioral neuroscience and psychiatry, since many …
Autism-associated 16p11. 2 microdeletion impairs prefrontal functional connectivity in mouse and human
Human genetic studies are rapidly identifying variants that increase risk for
neurodevelopmental disorders. However, it remains unclear how specific mutations impact …
neurodevelopmental disorders. However, it remains unclear how specific mutations impact …