Transfer RNA (tRNA) is present at tens of millions of transcripts in a human cell and is the
most abundant RNA in moles among all cellular RNAs. tRNA is also the most extensively …

Autoimmune subepidermal blistering diseases of the skin and mucosae constitute a large
group of sometimes devastating diseases, encompassing bullous pemphigoid, gestational …

Several decades of research have convincingly shown that classical human leukocyte
antigen (HLA) loci bear signatures of natural selection. Despite this conclusion, many …

Understanding natural selection is crucial to unveiling evolution of modern humans. Here,
we report natural selection signatures in the Japanese population using 2234 high-depth …

The major histocompatibility complex (MHC) is a large genetic region with many genes,
including the highly polymorphic classical class I and II genes that play crucial roles in …

Rainbow trout (Oncorhynchus mykiss) are widely cultured throughout the word for
commercial aquaculture. However, as a cold-water species, rainbow trout are highly …

Subepidermal autoimmune bullous diseases of the skin and mucosae comprise a large
group of chronic diseases, including bullous pemphigoid, pemphigoid gestationis, mucous …

Type 1 diabetes mellitus (T1D) is a complex autoimmune disorder characterised by loss of
the insulin-producing pancreatic beta cells in genetically predisposed individuals, ultimately …

Psoriasis is a complex immune-mediated inflammatory skin disease characterized by T-cell-
driven epidermal hyperplasia. It occurs on a strong genetic predisposition. The human …

The pool of transfer RNA (tRNA) molecules in cells allows the ribosome to decode genetic
information. This repertoire of molecular decoders is positioned in the crossroad of the …