Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Chronically implanted microelectrodes in the neural tissue elicit inflammatory responses that
are time varying and have been shown to depend on multiple factors. Among these factors …

The blood–brain barrier (BBB) consists of endothelial cells, astrocytes, and pericytes
embedded in basal lamina (BL). Most in vitro models use nonhuman, monolayer cultures for …

Aggregation and deposition of misfolded amyloid-β (Aβ) peptide in the brain is central to
Alzheimer's disease (AD). Oligomeric, protofibrillar, and fibrillar forms of Aβ are believed to …

A epilepsia é uma das doenças neurológicas crônicas mais comum em todo o mundo, e
apesar da diversidade de medicamentos disponíveis na prática clínica, um terço dos …

Central nervous system (CNS), being the most critical and sensitive organ in the human
body, necessitates a highly regulated extracellular environment, wherein the concentration …

La barrière hémato-encéphalique (BHE), constituée par les cellules endothéliales des
capillaires cérébraux (CECCs), est la principale interface d'échange entre le sang et le …