[HTML][HTML] Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases

AL Cardoso, A Fernandes, JA Aguilar-Pimentel… - Ageing research …, 2018 - Elsevier
Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Heparan sulfate as a therapeutic target in tauopathies: insights from zebrafish

SM Alavi Naini, N Soussi-Yanicostas - Frontiers in cell and …, 2018 - frontiersin.org
Microtubule-associated protein tau (MAPT) hyperphosphorylation and aggregation, are two
hallmarks of a family of neurodegenerative disorders collectively referred to as tauopathies …

Protofibrillar and fibrillar amyloid-β binding proteins in cerebrospinal fluid

MM Rahman, GT Westermark… - Journal of …, 2018 - content.iospress.com
Aggregation and deposition of misfolded amyloid-β (Aβ) peptide in the brain is central to
Alzheimer's disease (AD). Oligomeric, protofibrillar, and fibrillar forms of Aβ are believed to …

[引用][C] Towards frailty biomarkers Cardoso, Ana Luisa; Fernandes, Adelaide; Aguilar-Pimentel, Juan Antonio; de Angelis, Martin Hrabě; Guedes, Joana Ribeiro; Brito …

AL Cardoso - 2018