[HTML][HTML] Influence of pathogen and focus of infection on procalcitonin values in sepsis patients with bacteremia or candidemia

DO Thomas-Rüddel, B Poidinger, M Kott, M Weiss… - Critical care, 2018 - Springer
Background This study aimed to evaluate the accuracy of procalcitonin (PCT) serum
concentrations to diagnose Gram-negative bacteremia and the association of PCT serum …

[HTML][HTML] The use of procalcitonin in the determination of severity of sepsis, patient outcomes and infection characteristics

I Yunus, A Fasih, Y Wang - PloS one, 2018 - journals.plos.org
Objective The primary objective of this study was to determine the correlation between
procalcitonin values and illness severity by evaluating the degree of end organ dysfunction …

[HTML][HTML] A host-protein signature is superior to other biomarkers for differentiating between bacterial and viral disease in patients with respiratory infection and fever …

L Ashkenazi-Hoffnung, K Oved, R Navon… - European Journal of …, 2018 - Springer
Bacterial and viral infections often present with similar symptoms. Etiologic misdiagnosis can
alter the trajectory of patient care, including antibiotic overuse. A host-protein signature …

Pneumococcal community-acquired pneumonia detected by serotype-specific urinary antigen detection assays

RG Wunderink, WH Self, EJ Anderson… - Clinical Infectious …, 2018 - academic.oup.com
Background Streptococcus pneumoniae is considered the leading bacterial cause of
pneumonia in adults. Yet, it was not commonly detected by traditional culture-based and …

Initial inflammatory profile in community-acquired pneumonia depends on time since onset of symptoms

R Méndez, R Menéndez, C Cillóniz… - American Journal of …, 2018 - atsjournals.org
Rationale: Assessment of the inflammatory response can help the decision-making process
when diagnosing community-acquired pneumonia (CAP), but there is a lack of information …

Personalizing the management of pneumonia

S Gautam, L Sharma, CSD Cruz - Clinics in Chest …, 2018 - chestmed.theclinics.com
Lower respiratory tract infections (LRTIs) are the leading cause of death in developing
countries and account for more than 4 million deaths per year worldwide. 1 They result in the …

Sepsis and community-acquired pneumonia

A Ceccato, A Torres - Annals of Research Hospitals, 2018 - arh.amegroups.org
Community-acquired pneumonia (CAP) is a common disease and a leading cause of death.
CAP may cause local and systemic inflammation, leading to a dysregulated host response …

[HTML][HTML] A miRNA host response signature accurately discriminates acute respiratory infection etiologies

GD Poore, ER Ko, A Valente, R Henao… - Frontiers in …, 2018 - frontiersin.org
Background: Acute respiratory infections (ARIs) are the leading indication for antibacterial
prescriptions despite a viral etiology in the majority of cases. The lack of available …

Impact of procalcitonin guidance with an educational program on management of adults hospitalized with pneumonia

TL Walsh, BE DiSilvio, C Hammer, M Beg… - The American Journal of …, 2018 - Elsevier
Background Community-acquired pneumonia and healthcare-associated pneumonia are
often treated with prolonged antibiotic therapy. Procalcitonin (PCT) has effectively and safely …

Procalcitonin as a marker of etiology in adults hospitalized with community-acquired pneumonia

WH Self, RG Wunderink, S Jain… - Clinical Infectious …, 2018 - academic.oup.com
To the Editor—We appreciate the comments from Abers and Musher [1] in response to our
recent article describing the association between procalcitonin and etiology in community …