Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis

MC Silva, M Davoli-Ferreira, TS Medina… - Nature …, 2018 - nature.com
Chagas disease is caused by infection with the protozoan Trypanosoma cruzi (T. cruzi) and
is an important cause of severe inflammatory heart disease. However, the mechanisms …

Upregulation of Cardiac IL‐10 and Downregulation of IFN‐γ in Balb/c IL‐4−/− in Acute Chagasic Myocarditis due to Colombian Strain of Trypanosoma cruzi

MV da Silva, VL de Almeida… - Mediators of …, 2018 - Wiley Online Library
Inflammatory response in Chagas disease is related to parasite and host factors. However,
immune system regulation has not been fully elucidated. Thus, this study is aimed at …

Signaling pathways targeted by protozoan parasites to inhibit apoptosis

L Gutiérrez-Kobeh, JR González… - Current …, 2018 - books.google.com
Apoptosis is a biological process carried out during maturation, remodeling, growth, and
developmental processes in tissues, and also represents an important defense mechanism …

Who benefits from cellular immune response during the Chagas disease?

SP Vega-Royero, GJ Sibona - Biosystems, 2018 - Elsevier
We extend our previous model for the dynamical interaction between a mammal's immune
response and the Trypanosoma cruzi parasite during the acute phase of Chagas disease …

Efeitos do pré-tratamento com etanol na suscetibilidade à infecção por Trypanosoma cruzi, avaliada pelo perfil de citocinas produzidas por células apresentadoras de …

PHT Moura - 2018 - repositorio.unimontes.br
RESUMO A infecção por Trypanosoma cruzi (T. cruzi), induz resposta imune cuja eficiência
é importante para que a infecção persista ou seja eliminada. Com o consumo de etanol …