Clinical implications of in silico mathematical modeling for glioblastoma: a critical review

M Protopapa, A Zygogianni, GS Stamatakos… - Journal of neuro …, 2018 - Springer
Glioblastoma remains a clinical challenge in spite of years of extensive research. Novel
approaches are needed in order to integrate the existing knowledge. This is the potential …

[HTML][HTML] High-throughput binding affinity calculations at extreme scales

J Dakka, M Turilli, DW Wright, SJ Zasada… - BMC …, 2018 - Springer
Background Resistance to chemotherapy and molecularly targeted therapies is a major
factor in limiting the effectiveness of cancer treatment. In many cases, resistance can be …

A study on the predictability of acute lymphoblastic leukaemia response to treatment using a hybrid oncosimulator

E Ouzounoglou, E Kolokotroni, M Stanulla… - Interface …, 2018 - royalsocietypublishing.org
Efficient use of Virtual Physiological Human (VPH)-type models for personalized treatment
response prediction purposes requires a precise model parameterization. In the case where …