Aims This review provides an up‐to‐date curated source of information on alcohol, tobacco
and illicit drug use and their associated mortality and burden of disease. Limitations in the …

Background Major depressive disorder is one of the most common, burdensome, and costly
psychiatric disorders worldwide in adults. Pharmacological and non-pharmacological …

Summary Background The Global Burden of Diseases, Injuries, and Risk Factors Study
2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and …

Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown.
We conducted a multiancestry genome-wide-association meta-analysis in 521,612 …

Kidney disease has been described as the most neglected chronic disease. Reliable
estimates of the global burden of kidney disease require more population-based studies, but …

Purpose This article summarizes relevant findings related to low back and neck pain from
the Global Burden of Disease (GBD) reports for the purpose of informing the Global Spine …

Healthy ageing can be defined as “the process of developing and maintaining the functional
ability that enables wellbeing in older age”. Functional ability (ie, the health-related attributes …

Summary Background The protozoan Cryptosporidium is a leading cause of diarrhoea
morbidity and mortality in children younger than 5 years. However, the true global burden of …

Background How long one lives, how many years of life are spent in good and poor health,
and how the population's state of health and leading causes of disability change over time …

Adolescent growth and social development shape the early development of offspring from
preconception through to the post-partum period through distinct processes in males and …