Background Adolescence is a critical biological, psychological, and social developmental
stage involving heightened risk for substance use and associated adverse consequences …

A review of the scientific evidence on the effects of cannabinoids on brain and behavioral
functioning, with an emphasis on potential therapeutic use. The cannabis plant has been …

Objective: Deficits in reward processing are established in mood and substance use
disorders and are known risk factors for these disorders. Volume reductions of the …

Objective: Changes in gray matter volume and thickness are associated with adolescent
alcohol and cannabis use, but the impact of these substances on surface area remains …

Background Prevalence of marijuana (MJ) use among adolescents has been on the rise. MJ
use has been reported to impact several brain regions, including frontal regions such as the …

The current study examined whether age and frequent cannabis use interact to influence the
trajectories of positive and negative schizotypy over time. Participants were 155 cannabis …

The current study examined amygdala and orbitofrontal cortex (OFC) volumes as mediators
of the relationship between externalizing symptoms and daily smoking in adolescence …

The cannabinoid-1 receptor (CB1R) agonist Δ9-tetrahydrocannabinol (THC), the main
psychoactive constituent of cannabis, adversely effects working memory performance in …

W orldwide, most people start experimenting with drugs during the teenage years
(Degenhardt et al., 2008). Alcohol is the most popular drug among youth, with 21% of 12th …

From the time of conception until the time of death, the path of the human organism is
created and shaped by decisions. Some decisions we make ourselves, some are made for …