Precision nutrition for prevention and management of type 2 diabetes

DD Wang, FB Hu - The lancet Diabetes & endocrinology, 2018 - thelancet.com
Precision nutrition aims to prevent and manage chronic diseases by tailoring dietary
interventions or recommendations to one or a combination of an individual's genetic …

Interorgan metabolic crosstalk in human insulin resistance

S Gancheva, T Jelenik… - Physiological …, 2018 - journals.physiology.org
Excessive energy intake and reduced energy expenditure drive the development of insulin
resistance and metabolic diseases such as obesity and type 2 diabetes mellitus. Metabolic …

[PDF][PDF] Altered amino acid concentrations in NAFLD: Impact of obesity and insulin resistance

M Gaggini, F Carli, C Rosso, E Buzzigoli… - …, 2018 - Wiley Online Library
Plasma concentrations of amino acids (AAs), in particular, branched chain AAs (BCAAs), are
often found increased in nonalcoholic fatty liver disease (NAFLD); however, if this is due to …

Development, characterization and comparisons of targeted and non-targeted metabolomics methods

A Ribbenstedt, H Ziarrusta, JP Benskin - PLoS One, 2018 - journals.plos.org
The potential of a metabolomics method to detect statistically significant perturbations in the
metabolome of an organism is enhanced by excellent analytical precision, unequivocal …

Connection between BMI-related plasma metabolite profile and gut microbiota

F Ottosson, L Brunkwall, U Ericson… - The Journal of …, 2018 - academic.oup.com
Context Emerging evidence has related the gut microbiome and circulating metabolites to
human obesity. Gut microbiota is responsible for several metabolic functions, and altered …

Plant versus animal based diets and insulin resistance, prediabetes and type 2 diabetes: the Rotterdam Study

Z Chen, MG Zuurmond, N van der Schaft… - European journal of …, 2018 - Springer
Vegan or vegetarian diets have been suggested to reduce type 2 diabetes (T2D) risk.
However, not much is known on whether variation in the degree of having a plant-based …

Plasma lipidomic profiling and risk of type 2 diabetes in the PREDIMED trial

C Razquin, E Toledo, CB Clish, M Ruiz-Canela… - Diabetes …, 2018 - Am Diabetes Assoc
OBJECTIVE Specific lipid molecular changes leading to type 2 diabetes (T2D) are largely
unknown. We assessed lipidome factors associated with future occurrence of T2D in a …

[HTML][HTML] Short overview on metabolomics approach to study pathophysiology of oxidative stress in cancer

L Andrisic, D Dudzik, C Barbas, L Milkovic, T Grune… - Redox biology, 2018 - Elsevier
Association of oxidative stress with carcinogenesis is well known, but not understood well,
as is pathophysiology of oxidative stress generated during different types of anti-cancer …

Insulin resistance and glycine metabolism in humans

M Adeva-Andany, G Souto-Adeva… - Amino Acids, 2018 - Springer
Plasma glycine level is low in patients with obesity or diabetes and the improvement of
insulin resistance increases plasma glycine concentration. In prospective studies …

Long-term stability of human plasma metabolites during storage at− 80 C

M Haid, C Muschet, S Wahl… - Journal of proteome …, 2018 - ACS Publications
Prolonged storage of biospecimen can lead to artificially altered metabolite concentrations
and thus bias data analysis in metabolomics experiments. To elucidate the potential impact …