Selective vulnerability in neurodegenerative diseases

H Fu, J Hardy, KE Duff - Nature neuroscience, 2018 - nature.com
Neurodegenerative diseases have two general characteristics that are so fundamental we
usually take them for granted. The first is that the pathology associated with the disease only …

Disrupted striatal neuron inputs and outputs in Huntington's disease

A Reiner, YP Deng - CNS neuroscience & therapeutics, 2018 - Wiley Online Library
Huntington's disease (HD) is a hereditary progressive neurodegenerative disorder caused
by a CAG repeat expansion in the gene coding for the protein huntingtin, resulting in a …

Differential changes to D1 and D2 medium spiny neurons in the 12-month-old Q175+/- mouse model of Huntington's Disease

JW Goodliffe, H Song, A Rubakovic, W Chang… - PloS one, 2018 - journals.plos.org
Huntington's Disease (HD) is an autosomal dominant, progressive neurodegenerative
disorder caused by deleterious expansion of CAG repeats in the Huntingtin gene and …

[PDF][PDF] Alterations of neuronal activity and protein homeostasis in a mouse model of Huntington's disease

EK Schulz-Trieglaff - 2018 - edoc.ub.uni-muenchen.de
2.1. 1. Data generation __________________________________… 41 2.1. 2. More cells
are active in R6/2 mice at disease onset ________________________ 45 2.1. 3. Synaptic …

Study of the mTOR pathway in neurodegenerative diseases: from synapses to genes

N Martín Flores - 2018 - diposit.ub.edu
[eng] Huntington's disease (HD) and Parkinson's disease (PD) are devastating
neurodegenerative diseases that progress with the death of selective neuronal …

The Impact of Striatal Neuropeptides and Topography on Action Sequence Selection

D Buxton - 2018 - etheses.whiterose.ac.uk
Many common behaviours are a sequence of several actions. As action sequences are
learned their activation often becomes habitual, allowing smooth, rapid, and semi-automatic …

[引用][C] Qualitative und quantitative Analyse der Huntingtin-Aggregatbildung im transgenen Chorea-Huntington-Rattenmodell BACHD TG22

FJ Dieckmann - 2018 - Dissertation, Rostock, Universität …