Lung cancer is the leading cause of cancer-related mortality worldwide. Advances in our
understanding of the genomics of lung cancer have led to substantial progress in the …

We performed an extensive immunogenomic analysis of more than 10,000 tumors
comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across cancer …

MiRNAs, small non-coding RNA molecules, were recognized to be associated with the
incidence and development of diverse neoplasms. MiRNAs were small non-coding RNAs …

DNA methylation, especially in promoter regions, is a well-characterized epigenetic marker
related to gene expression regulation in eukaryotes. However, the role of intragenic DNA …

Background Breast cancer is one of the most common solid tumors in women involving
multiple subtypes. However, the mechanism for subtypes of breast cancer is still complicated …

Chronic, heavy alcohol consumption is associated with serious negative health effects,
including the development of several cancer types. One of the pathways affected by alcohol …

Inflammatory genes serve a crucial role in the pathogenesis of inflammation‑associated
tumors. However, as recent studies have mainly focused on the effects of single …

Substantial cancer genome sequencing efforts have discovered many important driver
genes contributing to tumorigenesis. However, very little is known about the genetic …

Characterizing functions of long noncoding RNAs (lncRNAs) remains a major challenge,
mostly due to the lack of lncRNA-involved regulatory relationships. A wide array of genome …

Although systematic genomic studies have identified a broad spectrum of non-coding RNAs
(ncRNAs) that are involved in breast cancer, our understanding of the epigenetic …