Type I interferons in tuberculosis: Foe and occasionally friend

L Moreira-Teixeira, K Mayer-Barber, A Sher… - Journal of Experimental …, 2018 - rupress.org
Tuberculosis remains one of the leading causes of mortality worldwide, and, despite its
clinical significance, there are still significant gaps in our understanding of pathogenic and …

The value of transcriptomics in advancing knowledge of the immune response and diagnosis in tuberculosis

A Singhania, RJ Wilkinson, M Rodrigue, P Haldar… - Nature …, 2018 - nature.com
Blood transcriptomics analysis of tuberculosis has revealed an interferon-inducible gene
signature that diminishes in expression after successful treatment; this promises improved …

[HTML][HTML] Impact of interferon-α receptor-1 promoter polymorphisms on the transcriptome of the hepatitis B virus-associated hepatocellular carcinoma

T Karamitros, G Papatheodoridis, D Paraskevis… - Frontiers in …, 2018 - frontiersin.org
Background and aims Genetic polymorphisms within the promoter of interferon-α receptor
type-1 (IFNAR1) have been associated with the susceptibility to and the outcome of chronic …

Interleukin-1 receptor antagonist mediates type I interferon-driven susceptibility to Mycobacterium tuberculosis

DX Ji, KJ Chen, N Mukaida, I Kramnik, KH Darwin… - bioRxiv, 2018 - biorxiv.org
Abstract The bacterium Mycobacterium tuberculosis (Mtb) causes tuberculosis (TB) and is
responsible for more human mortality than any other single pathogen. Although~ 1.7 billion …