Imaging the role of inflammation in mood and anxiety-related disorders

JC Felger - Current neuropharmacology, 2018 - ingentaconnect.com
Background: Studies investigating the impact of a variety of inflammatory stimuli on the brain
and behavior have reported evidence that inflammation and release of inflammatory …

Early life stress, air pollution, inflammation, and disease: an integrative review and immunologic model of social-environmental adversity and lifespan health

HAO Alvarez, LD Kubzansky, MJ Campen… - Neuroscience & …, 2018 - Elsevier
Socially disadvantaged individuals are at greater risk for simultaneously being exposed to
adverse social and environmental conditions. Although the mechanisms underlying joint …

Maternal systemic interleukin-6 during pregnancy is associated with newborn amygdala phenotypes and subsequent behavior at 2 years of age

AM Graham, JM Rasmussen, MD Rudolph, CM Heim… - Biological …, 2018 - Elsevier
Background Maternal inflammation during pregnancy increases the risk for offspring
psychiatric disorders and other adverse long-term health outcomes. The influence of …

[HTML][HTML] Childhood victimization and inflammation in young adulthood: a genetically sensitive cohort study

JR Baldwin, L Arseneault, A Caspi, HL Fisher… - Brain, behavior, and …, 2018 - Elsevier
Objective Childhood victimization is an important risk factor for later immune-related
disorders. Previous evidence has demonstrated that childhood victimization is associated …

Future directions in the study of early-life stress and physical and emotional health: implications of the neuroimmune network hypothesis

CE Hostinar, R Nusslock, GE Miller - Journal of clinical child & …, 2018 - Taylor & Francis
Early-life stress is associated with increased vulnerability to physical and emotional health
problems across the lifespan. The recently developed neuroimmune network hypothesis …

[HTML][HTML] Adverse childhood experiences and adult inflammation: Findings from the 1958 British birth cohort

M Chen, RE Lacey - Brain, behavior, and immunity, 2018 - Elsevier
Background The relationship between adverse childhood experiences (ACE) and poorer
health across the life course is well established. Increased chronic inflammation might be …

Weathering the storm; a review of pre-pregnancy stress and risk of spontaneous abortion

T Frazier, CJR Hogue, EA Bonney, KM Yount… - …, 2018 - Elsevier
Abstract The Weathering Effect is a theory that links stress exposure, over the life-course,
with racial disparities in reproductive outcomes, through the effects of social adversity on a …

Inflammation-related epigenetic risk and child and adolescent mental health: A prospective study from pregnancy to middle adolescence

ED Barker, CAM Cecil, E Walton… - Development and …, 2018 - cambridge.org
In 785 mother–child (50% male) pairs from a longitudinal epidemiological birth cohort, we
investigated associations between inflammation-related epigenetic polygenic risk scores (i …

Biomarkers for depression: recent insights, current challenges and future prospects

R Strawbridge, AH Young, AJ Cleare - Focus, 2018 - Am Psychiatric Assoc
A plethora of research has implicated hundreds of putative biomarkers for depression, but
has not yet fully elucidated their roles in depressive illness or established what is abnormal …

A novel variant in TAF1 affects gene expression and is associated with X-linked TAF1 intellectual disability syndrome

SE Hurst, E Liktor-Busa, A Moutal, S Parker… - Neuronal …, 2018 - portlandpress.com
We investigated the genome of a 5-year-old male who presented with global developmental
delay (motor, cognitive, and speech), hypotonia, possibly ataxia, and cerebellar hypoplasia …