Direct control of stem cell behavior using biomaterials and genetic factors

JK Yoon, ML Kang, JH Park, KM Lee… - Stem Cells …, 2018 - Wiley Online Library
Stem cells have recently emerged as an important candidate for cell therapy. However,
some major limitations still exist such as a small quantity of cell supply, senescence, and …

Small molecules for neural stem cell induction

D Liu, N Pavathuparambil Abdul Manaph… - Stem Cells and …, 2018 - liebertpub.com
Generation of induced pluripotent stem cells (iPSCs) from other somatic cells has provided
great hopes for transplantation therapies. However, these cells still cannot be used for …

Generation of transgene-free porcine intermediate type induced pluripotent stem cells

D Li, J Secher, P Hyttel, M Ivask, M Kolko, VJ Hall… - Cell Cycle, 2018 - Taylor & Francis
Physiologically and anatomically, humans and pigs share many similarities, which make
porcine induced pluripotent stem cells (piPSCs) very attractive for modeling human cell …

Reproductive technologies for the generation and maintenance of valuable animal strains

T Kaneko - Journal of Reproduction and Development, 2018 - jstage.jst.go.jp
Many types of mutant and genetically engineered strains have been produced in various
animal species. Their numbers have dramatically increased in recent years, with new strains …

Permissiveness to form pluripotent stem cells may be an evolutionarily derived characteristic in Mus musculus

TA Garbutt, TI Konneker, K Konganti, AE Hillhouse… - Scientific Reports, 2018 - nature.com
Mus musculus is the only known species from which embryonic stem cells (ESC) can be
isolated under conditions requiring only leukemia inhibitory factor (LIF). Other species are …

Induced pluripotent stem cells (iPSCs) as model to study inherited defects of neurotransmission in inborn errors of metabolism

S Jung-Klawitter, T Opladen - Journal of Inherited Metabolic Disease, 2018 - Springer
The ability to reprogram somatic cells to induced pluripotent stem cells (iPSCs) has
revolutionized the way of modeling human disease. Especially for the modeling of rare …

Culture medium for preparing neural stem cells and use thereof

G Pan, D Pei, L Wang, L Wang, Y Xue - US Patent 10,011,819, 2018 - Google Patents
Provided are a culture medium for preparing neural stem cell and use thereof, the culture
medium for preparing neural stem cell comprising: a basic culture medium suitable for the …

The development of methods for primary mast cells in vitro and ex vivo: An historical review

T Yu, Z He, M Yang, J Song, C Ma, S Ma, J Feng… - Experimental Cell …, 2018 - Elsevier
Mast cells (MCs) are tissue-based stationary effector cells that form the immune system's first-
line defense against various challenges. They are developed from the bone marrow-derived …

Generation of functional cardiomyocytes from rat embryonic and induced pluripotent stem cells using feeder-free expansion and differentiation in suspension culture

J Dahlmann, G Awad, C Dolny, S Weinert, K Richter… - PLoS …, 2018 - journals.plos.org
The possibility to generate cardiomyocytes from pluripotent stem cells in vitro has enormous
significance for basic research, disease modeling, drug development and heart repair. The …

整合素和E-钙黏素在诱导多能干细胞重编程及干性维持中的作用

胡若文, 陈晓芳 - 中国组织工程研究, 2018 - cjter.com
摘要背景: 诱导多能干细胞在疾病模型和再生医学领域具有广阔的应用前景,
能够利用安全高效的方法进行体细胞重编程是诱导多能干细胞广泛应用于临床的前提 …