RNA‐binding proteins (RBPs) and noncoding (nc) RNAs (such as microRNAs, long
ncRNAs, and others) cooperate within a post‐transcriptional network to regulate the …

Establishing and maintaining the complex network of connections required for neuronal
communication requires the transport and in situ translation of large groups of mRNA s to …

RNA-binding proteins (RBPs) are expressed broadly during both development and
malignant transformation, yet their mechanistic roles in epithelial homeostasis or as drivers …

Cytokines and cytokine signaling pathways are crucial for regulating cellular functions,
including cell growth, proliferation, differentiation, and cell death. Cytokines regulate …

Ribonucleoprotein complexes, which contain mRNA s and their regulator proteins, carry out
post‐transcriptional control of gene expression. The function of many RNA‐binding proteins …

The 21st annual meeting of the Portuguese Society of Human Genetics (SPGH), organized
by Luísa Romão, Ana Sousa and Rosário Pinto Leite, was held in Caparica, Portugal, from …

Estrogen receptor alpha (ERα) activity is associated with increased cancer cell proliferation.
Studies aiming to understand the impact of ERα on cancer-associated phenotypes have …

The intestinal epithelium spans proliferating crypts at its base to differentiated villi at the
luminal surface and renews itself every 3-5 days. It maintains a dynamic equilibrium …

Proper control of mRNA stability is key in the regulation of gene expression, with half-lives
varying considerably transcriptome-wide. While sequence elements regulating mRNA decay …

The goal of this research was to elucidate the individual and cooperative role of oncogenes
within the frequently amplified 8p12-11 genomic locus which is known to predict poor …