Fifteen years of LIFE (Losartan Intervention for Endpoint Reduction in Hypertension)—Lessons learned for losartan: An “old dog playing good tricks”

N Katsiki, K Tsioufis, D Ural… - The Journal of Clinical …, 2018 - Wiley Online Library
There is an unmet need to prevent cardiovascular disease and chronic kidney disease
development and progression worldwide. Losartan, the first angiotensin receptor blocker …

How to improve effectiveness and adherence to antihypertensive drug therapy: central role of dihydropyridinic calcium channel blockers in hypertension

G Tocci, G Desideri, E Roca, C Calcullo… - High Blood Pressure & …, 2018 - Springer
Essential hypertension is a complex clinical condition, characterized by multiple and
concomitant abnormal activation of different regulatory and contra-regulatory …

Drug adherence in hypertension and cardiovascular protection

M Burnier - 2018 - Springer
When asked about the difficulties encountered in the management of patients with
cardiovascular risk factors such as hypertension, dyslipidemia, and diabetes, most practicing …

Natural history of treated and untreated hypertension

M Volpe, C Savoia - Disorders of blood pressure regulation: phenotypes …, 2018 - Springer
Hypertension is a major modifiable risk factor for the development of cardiovascular,
cerebrovascular, and renal diseases and represents a significant public health concern …

Use of Fixed-Dose Combinations in Hypertension and Cardiovascular Disease Prevention

M Volpe, G Tocci, G Gallo - Drug Adherence in Hypertension and …, 2018 - Springer
In spite of the wide availability of effective and well-tolerated antihypertensive drugs, the
proportions of treated hypertensive patients achieving the recommended BP targets are …