Summary The WhiB‐like (Wbl) family of proteins are exclusively found in Actinobacteria.
Wbls have been shown to play key roles in virulence and antibiotic resistance in …

Protein synthesis is a fundamental requirement of all cells for survival and replication. To
date, vast numbers of genetic and biochemical studies have been performed to address the …

Members of the Mycobacterium tuberculosis complex (MTBC) are the causative agents of
tuberculosis in a range of mammals, including humans. A key feature of MTBC pathogens is …

Isoniazid (INH) and ethambutol (EMB) are two major first-line drugs for managing
tuberculosis (TB), caused by the microbe Mycobacterium tuberculosis. Although co-use of …

Tuberculosis is the leading killer among infectious diseases worldwide. Increasing multidrug
resistance has prompted new approaches for tuberculosis drug development, including …

The biological processes regulated by the essential response regulator MtrA and the growth
conditions promoting its activation in Mycobacterium tuberculosis, a slow grower and …

Th17 cells are major players in multiple autoimmune diseases and are developmentally
contingent on reciprocal functionality between the transcription factor Retineic acid receptor …

Iron–sulphur (Fe-S) clusters are ubiquitous co-factors which require multi-protein systems for
their synthesis. In Mycobacterium tuberculosis, the Rv1460-Rv1461-Rv1462-Rv1463-csd …

Tuberculosis is a global health problem, with a third of the world's population infected with
the bacillus, Mycobacterium tuberculosis. The problem is exacerbated by the emergence of …

Nucleoid associated proteins (NAPs) are known organisers of chromosomal structure and
regulators of transcriptional expression. The number of proposed NAPs in mycobacteria are …