The main inconvenience of conventional eye drops is the rapid washout of the drugs due to nasolacrimal drainage or ophthalmic barriers. The ocular drug bioavailability can be …
EMA Hejjaji, AM Smith, GA Morris - International journal of biological …, 2018 - Elsevier
Mucoadhesive molecules such as chitosan, can allow targeting of a particular tissue to prolong residence time and subsequently improve bioavailability. The purpose of this study …
J Li, S Tian, Q Tao, Y Zhao, R Gui, F Yang… - International journal …, 2018 - Taylor & Francis
Background To date, the rapid clearance from ocular surface has been a huge obstacle for using eye drops to treat glaucoma, since it has led to the short preocular residence time and …
Polymer-based eye drops are the most used drug delivery system to treat dry eye disease (DED). Therefore, the mucoadhesion between the polymer and the ocular mucin is crucial to …
S Rossi, B Vigani, MC Bonferoni, G Sandri… - … of Pharmaceutical and …, 2018 - Elsevier
At the end of 80s and in the early 90s, an increasing interest in the development of mucoadhesive formulations occurred in the pharmaceutical field. Such formulations …
Raloxifene (RXF) is a hormone-like medication used for treating postmenopausal osteoporosis and estrogen-dependent breast cancer, yet associated with bad low …
M Montenegro-Nicolini, PE Reyes, MO Jara… - AAPS …, 2018 - Springer
The buccal mucosa appears as a promissory route for biologic drug administration, and pharmaceutical films are flexible dosage forms that can be used in the buccal mucosa as …
B Khatun, N Banik, A Hussain… - Journal of …, 2018 - Taylor & Francis
Here, we have reported the influence of MMT and genipin in releasing curcumin from the Genipin crosslinked Chitosan/MMT nanoparticles, prepared by ionic gelation method. The …
L Dai, W Zhu, C Si, J Lei - International journal of molecular sciences, 2018 - mdpi.com
Panax ginseng has high medicinal and health values. However, the various and complex components of ginseng may interact with each other, thus reducing and even reversing …