[HTML][HTML] Nano based drug delivery systems: recent developments and future prospects

JK Patra, G Das, LF Fraceto, EVR Campos… - Journal of …, 2018 - Springer
Nanomedicine and nano delivery systems are a relatively new but rapidly developing
science where materials in the nanoscale range are employed to serve as means of …

[HTML][HTML] Strategies for improving ocular drug bioavailability and corneal wound healing with chitosan-based delivery systems

T Irimia, MV Ghica, L Popa, V Anuţa, AL Arsene… - Polymers, 2018 - mdpi.com
The main inconvenience of conventional eye drops is the rapid washout of the drugs due to
nasolacrimal drainage or ophthalmic barriers. The ocular drug bioavailability can be …

Evaluation of the mucoadhesive properties of chitosan nanoparticles prepared using different chitosan to tripolyphosphate (CS: TPP) ratios

EMA Hejjaji, AM Smith, GA Morris - International journal of biological …, 2018 - Elsevier
Mucoadhesive molecules such as chitosan, can allow targeting of a particular tissue to
prolong residence time and subsequently improve bioavailability. The purpose of this study …

Montmorillonite/chitosan nanoparticles as a novel controlled-release topical ophthalmic delivery system for the treatment of glaucoma

J Li, S Tian, Q Tao, Y Zhao, R Gui, F Yang… - International journal …, 2018 - Taylor & Francis
Background To date, the rapid clearance from ocular surface has been a huge obstacle for
using eye drops to treat glaucoma, since it has led to the short preocular residence time and …

[HTML][HTML] Useful in vitro techniques to evaluate the mucoadhesive properties of hyaluronic acid-based ocular delivery systems

A Graça, LM Gonçalves, S Raposo, HM Ribeiro… - Pharmaceutics, 2018 - mdpi.com
Polymer-based eye drops are the most used drug delivery system to treat dry eye disease
(DED). Therefore, the mucoadhesion between the polymer and the ocular mucin is crucial to …

Rheological analysis and mucoadhesion: A 30 year-old and still active combination

S Rossi, B Vigani, MC Bonferoni, G Sandri… - … of Pharmaceutical and …, 2018 - Elsevier
At the end of 80s and in the early 90s, an increasing interest in the development of
mucoadhesive formulations occurred in the pharmaceutical field. Such formulations …

[HTML][HTML] Raloxifene/SBE-β-CD inclusion complexes formulated into nanoparticles with chitosan to overcome the absorption barrier for bioavailability enhancement

Z Wang, Y Li - Pharmaceutics, 2018 - mdpi.com
Raloxifene (RXF) is a hormone-like medication used for treating postmenopausal
osteoporosis and estrogen-dependent breast cancer, yet associated with bad low …

The effect of inkjet printing over polymeric films as potential buccal biologics delivery systems

M Montenegro-Nicolini, PE Reyes, MO Jara… - AAPS …, 2018 - Springer
The buccal mucosa appears as a promissory route for biologic drug administration, and
pharmaceutical films are flexible dosage forms that can be used in the buccal mucosa as …

Genipin crosslinked curcumin loaded chitosan/montmorillonite K-10 (MMT) nanoparticles for controlled drug delivery applications

B Khatun, N Banik, A Hussain… - Journal of …, 2018 - Taylor & Francis
Here, we have reported the influence of MMT and genipin in releasing curcumin from the
Genipin crosslinked Chitosan/MMT nanoparticles, prepared by ionic gelation method. The …

[HTML][HTML] “Nano-ginseng” for enhanced cytotoxicity against cancer cells

L Dai, W Zhu, C Si, J Lei - International journal of molecular sciences, 2018 - mdpi.com
Panax ginseng has high medicinal and health values. However, the various and complex
components of ginseng may interact with each other, thus reducing and even reversing …