Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases

M Jucker, LC Walker - Nature neuroscience, 2018 - nature.com
Many neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis, are characterized by the progressive appearance of abnormal …

Prion-like properties of disease-relevant proteins in amyotrophic lateral sclerosis

S Bräuer, V Zimyanin, A Hermann - Journal of Neural Transmission, 2018 - Springer
The hallmark of age-related neurodegenerative diseases is the appearance of cellular
protein deposits and spreading of this pathology throughout the central nervous system …

[HTML][HTML] The prion protein is embedded in a molecular environment that modulates transforming growth factor β and integrin signaling

F Ghodrati, M Mehrabian, D Williams, O Halgas… - Scientific Reports, 2018 - nature.com
At times, it can be difficult to discern if a lack of overlap in reported interactions for a protein-
of-interest reflects differences in methodology or biology. In such instances, systematic …

Прионные заболевания человека: современные аспекты

НН Заваденко, ГШ Хондкарян, РЦ Бембеева… - Журнал неврологии и …, 2018 - elibrary.ru
Прионные заболевания, или трансмиссивные губкообразные энцефалопатии—группа
нейродегенераций, характеризующихся быстро прогрессирующими деменцией и …

[HTML][HTML] Low mood, visual hallucinations, and falls–heralding the onset of rapidly progressive probable sporadic Creutzfeldt–Jakob disease in a 73-year old: a case …

DM Klotz, RS Penfold - Journal of medical case reports, 2018 - Springer
Abstract Background Creutzfeldt–Jakob disease is a rare and rapidly fatal
neurodegenerative disease. Since clinicians may see only very few cases during their …

Kiire kuluga dementsus, mis osutus Creutzfeldti-Jakobi tõveks: haigusjuhu kirjeldus

A Milovidov, T Matsalu, M Kaarlõp, T Toomsoo - Eesti Arst, 2018 - ojs.utlib.ee
Prioonhaigused on haruldased neurodegeneratiivsed haigused, mis põhjustavad kiire
kuluga dementsuse ja lõpevad alati surmaga. Creutzfeldti-Jakobi tõbi kuulub prioonhaiguste …

[PDF][PDF] Regional-dependent, Comprehensive Characterization of MiRNA Signatures in Sporadic Creutzfeldt-Jakob Disease and Early Alzheimer's Disease-type …

K Thüne - 2018 - ediss.uni-goettingen.de
The pathogenic mechanisms and the origins of neurodegenerative diseases remain unclear
on molecular level. Increasing evidences postulate alterations in miRNA signatures as …

Influencia de la región n-terminal de la proteína del prion en la susceptibilidad al mal plegamiento, mantenimiento de las características de la cepa y neurotoxicidad.

V Venegas García - 2018 - addi.ehu.es
Las enfermedades priónicas, también conocidas como encefalopatías espongiformes
transmisibles (EETs), son enfermedades neurodegenerativas que afectan a humanos y …

[HTML][HTML] Autofagia y biomarcadores en las enfermedades priónicas

Ó López-Pérez, R Bolea Bailo, I Martín Burriel - 2018 - zaguan.unizar.es
Las encefalopatías espongiformes transmisibles (EETs), o enfermedades priónicas, son un
grupo de trastornos neurodegenerativos fatales que afectan a los animales y al hombre …

Effect of congruent gastro-intestinal pathogen infection on oral prion disease susceptibility

A Sánchez Quintero - 2018 - era.ed.ac.uk
Transmissible spongiform encephalopathies (TSEs) or prion diseases, are subacute
neurodegenerative diseases that infect humans and animals. Many of these diseases are …