Overcoming the blood–brain barrier: the role of nanomaterials in treating neurological diseases

D Furtado, M Björnmalm, S Ayton, AI Bush… - Advanced …, 2018 - Wiley Online Library
Therapies directed toward the central nervous system remain difficult to translate into
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …

Crossing the blood-brain barrier with nanoparticles

Y Zhou, Z Peng, ES Seven, RM Leblanc - Journal of controlled release, 2018 - Elsevier
The blood-brain barrier (BBB) is one of the most essential protection mechanisms in the
central nervous system (CNS). It selectively allows individual molecules such as small lipid …

[HTML][HTML] Nanotherapeutics: An insight into healthcare and multi-dimensional applications in medical sector of the modern world

M Prasad, UP Lambe, B Brar, I Shah… - Biomedicine & …, 2018 - Elsevier
In recent years nanotechnology has revolutionized the healthcare strategies and envisioned
to have a tremendous impact to offer better health facilities. In this context, medical …

Inorganic nanoparticles for cancer therapy: a transition from lab to clinic

S Bayda, M Hadla, S Palazzolo, P Riello… - Current medicinal …, 2018 - ingentaconnect.com
Background: Inorganic nanoparticles (NPs) including those derived from metals (eg, gold,
silver), semiconductors (eg, quantum dots), carbon dots, carbon nanotubes, or oxides (eg …

[HTML][HTML] Phyto-therapeutic and nanomedicinal approaches to cure Alzheimer's disease: present status and future opportunities

M Ovais, N Zia, I Ahmad, AT Khalil, A Raza… - Frontiers in aging …, 2018 - frontiersin.org
Alzheimer's disease (AD) is characterized by cognitive inability manifested due to the
accumulation of β-amyloid, formation of hyper phosphorylated neurofibrillary tangles, and a …

Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases

N Shah, AS Mohammad, P Saralkar, SA Sprowls… - Pharmacological …, 2018 - Elsevier
In women, breast cancer is the most common cancer diagnosis and second most common
cause of cancer death. More than half of breast cancer patients will develop metastases to …

Non-viral gene therapy using multifunctional nanoparticles: status, challenges, and opportunities

G Lin, L Li, N Panwar, J Wang, SC Tjin, X Wang… - Coordination Chemistry …, 2018 - Elsevier
Gene delivery for molecular-level therapeutics is regarded as a prospective remedial route
to cure human diseases by the medical community. The major challenge for delivering …

Enhanced permeability of blood–brain barrier and targeting function of brain via borneol-modified chemically solid lipid nanoparticle

H Song, M Wei, N Zhang, H Li, X Tan… - International journal …, 2018 - Taylor & Francis
Introduction The incidence of central nervous system disease has increased in recent years.
However, the transportation of drug is restricted by the blood–brain barrier, contributing to …

[HTML][HTML] RETRACTED ARTICLE: In vitro evaluation of the toxic effects of MgO nanostructure in Hela cell line

MW Akram, M Fakhar-e-Alam, M Atif, AR Butt… - Scientific reports, 2018 - nature.com
MgO is an attractive choice for carcinogenic cell destruction in photodynamic therapy, as
confirmed by manifold analysis. The prime focus of the presented research is to investigate …

Calibration-free relaxation-based multi-color magnetic particle imaging

Y Muslu, M Utkur, OB Demirel… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
Magnetic particle imaging (MPI) is a novel imaging modality with important potential
applications, such as angiography, stem cell tracking, and cancer imaging. Recently, there …