[HTML][HTML] The effect of ethanolic extract of Thymus kotschyanus on cancer cell growth in vitro and depression-like behavior in the mouse
MH Doosti, K Ahmadi, M Fasihi-Ramandi - Journal of traditional and …, 2018 - Elsevier
Cancer and depression are known as two of the most debilitating disease and disorder
increasing evidence suggest an urgent need for new therapeutic agents with lower toxicity …
increasing evidence suggest an urgent need for new therapeutic agents with lower toxicity …
[HTML][HTML] Tert-butyl 4-((1-phenyl-1H-pyrazol-4-yl) methyl) piperazine-1-carboxylate (LQFM104)–new piperazine derivative with antianxiety and antidepressant-like …
DM da Silva, G Sanz, BG Vaz, FS de Carvalho… - Biomedicine & …, 2018 - Elsevier
The piperazine derivatives correspond to an extensive chemical class of compounds with
numerous neuropharmacological activities, including antidepressant (eg, nefazodone …
numerous neuropharmacological activities, including antidepressant (eg, nefazodone …
Impairing of serotonin synthesis by p-chlorphenylanine prevents the forgetting of contextual memory after reminder and the protein synthesis inhibition
IB Deryabina, LN Muranova, VV Andrianov… - Frontiers in …, 2018 - frontiersin.org
HIGHLIGHTS The injection of p-chlorophenylalanine, specific blocker of 5-HT synthesis 3
days before reminder with anisomycin administration prevented forgetting. It is known that …
days before reminder with anisomycin administration prevented forgetting. It is known that …
An extract of Synedrella nodiflora (L) Gaertn exhibits antidepressant properties through monoaminergic mechanisms
Synedrella nodiflora (SNE) has been used traditionally for many neurological conditions and
some of these neuroactive effects have been scientifically substantiated. The usefulness of …
some of these neuroactive effects have been scientifically substantiated. The usefulness of …
Synergistic action of sodium selenite with some antidepressants and diazepam in mice
E Kędzierska, L Dąbkowska, P Obierzyński… - Pharmaceutics, 2018 - mdpi.com
Background: The antidepressant and anxiolytic effects of selenium (Se) have been proven in
many studies. This work was aimed at confirming these activities of its inorganic form …
many studies. This work was aimed at confirming these activities of its inorganic form …
A new piperazine derivative: 1-(4-(3,5-di-tert-butyl-4-hydroxybenzyl) piperazin-1-yl)-2-methoxyethan-1-one with antioxidant and central activity
AF Brito, PCCS Braga, LKS Moreira, DM Silva… - Naunyn-Schmiedeberg's …, 2018 - Springer
In the scope of a research program aimed at developing new drugs for the treatment of
central nervous system diseases, we describe herein the synthesis and pharmacological …
central nervous system diseases, we describe herein the synthesis and pharmacological …
Chronic paroxetine treatment prevents disruption of methamphetamine-sensitive circadian oscillator in a transgenic mouse model of Huntington's disease
K Ouk, J Aungier, M Cuesta, AJ Morton - Neuropharmacology, 2018 - Elsevier
Circadian abnormalities seen in Huntington's disease (HD) patients are recapitulated in
several HD transgenic mouse models. In mice, alongside the master clock located in the …
several HD transgenic mouse models. In mice, alongside the master clock located in the …
[PDF][PDF] A study on antidepressant-like effect of dihydroxy flavones in mice and their mechanisms involved
N Panneerselvam, J Shanmugasundaram… - National Journal of …, 2018 - njppp.com
Background: In the treatment of depression, drugs with a quick onset of action and high
margin of safety are intensely being searched. Previous studies indicate flavonoids as a …
margin of safety are intensely being searched. Previous studies indicate flavonoids as a …
Differential roles of specific sub-regions of the longitudinal axis of the hippocampus in the behavioural and neurogenesis responses to stress and antidepressant …
B Rocha Levone - 2018 - cora.ucc.ie
Accumulating evidence suggests that the hippocampus is functionally segregated along its
longitudinal axis into a dorsal (dHi) and a ventral sub-region (vHi). Indeed, recent gene …
longitudinal axis into a dorsal (dHi) and a ventral sub-region (vHi). Indeed, recent gene …
[PDF][PDF] Supplemental Table Legend
Supplemental Information: The mouse as a model for neuropsychiatric drug development James
R. Howe VI, Mark F. Bear, Peyman Gols Page 1 Supplemental Information: The mouse as a …
R. Howe VI, Mark F. Bear, Peyman Gols Page 1 Supplemental Information: The mouse as a …