Access to effective affordable contraception is critical for individual and public health. A wide
range of hormonal contraceptives (HCs), which differ in composition, concentration of the …

While significant progress has been made in terms of human immunodeficiency virus (HIV)
therapy, treatment does not represent a cure and remains inaccessible to many people …

Fibroblastic reticular cells (FRCs) are stromal cells in secondary lymphoid organs, the major
sites for HIV-1 infection of CD4+ T cells. Although FRCs regulate T cell survival, proliferation …

Objectives Localized provoked vulvodynia (LPV) afflicts approximately 8% of women in the
United States and represents a huge financial, physical, and psychological burden. Women …

Introduction: HIV affects more women than any other life-threatening infectious agent, and
most infections are sexually transmitted. HIV must breach the female genital tract mucosal …

Problem The contribution of fibroblasts to innate immune protection of the human female
reproductive tract (FRT) against viral pathogens is relatively unknown. Method of Study …

Despite its anatomical location, the ovary is a site of pathogen exposure in the human
female reproductive tract (FRT). However, the role of ovarian stromal fibroblasts in immune …

Background An HIV cure has not yet been achieved because latent viral reservoirs persist,
particularly in resting CD4+ T lymphocytes. In vitro, it is difficult to infect resting CD4+ T cells …

Problem Genital epithelial cells (GEC s) line the mucosal surface of the female genital tract
(FGT) and are the first cells that interface with both commensal microbiota and sexually …

Seminal plasma (SP), the liquid fraction of semen, is not mandatory for conception, but
clinical studies suggest that SP improves implantation rates. Prior in vitro studies examining …