[PDF][PDF] Modular organization and assembly of SWI/SNF family chromatin remodeling complexes
Summary Mammalian SWI/SNF (mSWI/SNF) ATP-dependent chromatin remodeling
complexes are multi-subunit molecular machines that play vital roles in regulating genomic …
complexes are multi-subunit molecular machines that play vital roles in regulating genomic …
[HTML][HTML] A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells
The role of individual subunits in the targeting and function of the mammalian BRG1-
associated factors (BAF) complex in embryonic stem cell (ESC) pluripotency maintenance …
associated factors (BAF) complex in embryonic stem cell (ESC) pluripotency maintenance …
Fetal hemoglobin induction by epigenetic drugs
D Lavelle, JD Engel, Y Saunthararajah - Seminars in hematology, 2018 - Elsevier
Fetal hemoglobin (HbF) inhibits the root cause of sickle pathophysiology, sickle hemoglobin
polymerization. Individuals who naturally express high levels of HbF beyond infancy thus …
polymerization. Individuals who naturally express high levels of HbF beyond infancy thus …
Disruption of mammalian SWI/SNF and polycomb complexes in human sarcomas: mechanisms and therapeutic opportunities
MJ McBride, C Kadoch - The Journal of pathology, 2018 - Wiley Online Library
Soft‐tissue sarcomas are increasingly characterized and subclassified by genetic
abnormalities that represent underlying drivers of their pathology. Hallmark tumor …
abnormalities that represent underlying drivers of their pathology. Hallmark tumor …
[HTML][HTML] Targeting AURKA-CDC25C axis to induce synthetic lethality in ARID1A-deficient colorectal cancer cells
ARID1A, a component of the SWI/SNF chromatin remodeling complex, is a tumor suppressor
with a high frequency of inactivating mutations in many cancers. Therefore, ARID1A …
with a high frequency of inactivating mutations in many cancers. Therefore, ARID1A …
Regulation of ATP-dependent chromatin remodelers: accelerators/brakes, anchors and sensors
S Paul, B Bartholomew - Biochemical Society Transactions, 2018 - portlandpress.com
All ATP-dependent chromatin remodelers have a DNA translocase domain that moves along
double-stranded DNA when hydrolyzing ATP, which is the key action leading to DNA …
double-stranded DNA when hydrolyzing ATP, which is the key action leading to DNA …
SMARCB1 deficiency integrates epigenetic signals to oncogenic gene expression program maintenance in human acute myeloid leukemia
SWI/SNF is an evolutionarily conserved multi-subunit chromatin remodeling complex that
regulates epigenetic architecture and cellular identity. Although SWI/SNF genes are altered …
regulates epigenetic architecture and cellular identity. Although SWI/SNF genes are altered …
Architecture of SWI/SNF chromatin remodeling complex
Z Zhang, X Wang, J Xin, Z Ding, S Liu, Q Fang… - Protein & …, 2018 - academic.oup.com
The SWI/SNF complex is a large ATP-dependent chromatin remodeling complex that is
highly conserved from yeast to human, which is essential for transcription regulation …
highly conserved from yeast to human, which is essential for transcription regulation …
Evolution and expression of core SWI/SNF genes in red algae
Red algae are the oldest identifiable multicellular eukaryotes, with a fossil record dating
back more than a billion years. During that time two major rhodophyte lineages …
back more than a billion years. During that time two major rhodophyte lineages …
[PDF][PDF] DR. JOHN W STILLER (Orcid ID: 0000-0002-0668-8243)
JW Stiller, C Yang, J Collén, N Kowalczyk… - scholarworks.iupui.edu
Red algae are the oldest identifiable multicellular eukaryotes, with a fossil record dating
back more than a billion years. During that time two major rhodophyte lineages …
back more than a billion years. During that time two major rhodophyte lineages …