Andrographolide protects PC12 cells against β-amyloid-induced autophagy-associated cell death through activation of the Nrf2-mediated p62 signaling pathway

L Gu, Q Yu, Q Li, L Zhang, H Lu, X Zhang - International Journal of …, 2018 - mdpi.com
Recent studies mentioned that Andrographolide (Andro), the main bioactive component of
traditional Chinese medicine Andrographis paniculata, may be a potential natural product …

A hispanolone-derived diterpenoid inhibits M2-Macrophage polarization in vitro via JAK/STAT and attenuates chitin induced inflammation in vivo

L Jiménez-García, MÁ Higueras, S Herranz… - Biochemical …, 2018 - Elsevier
Macrophages are highly plastic cells that adopt different functional phenotypes in response
to environmental signals. Classically activated macrophages (M1) exhibit a pro-inflammatory …

Andrographolide inhibits chikungunya virus infection by up-regulating host innate immune pathways

S Gupta, KP Mishra, PK Dash, M Parida… - Asian Pacific Journal …, 2018 - journals.lww.com
Objective: To investigate the therapeutic efficacy of andrographolide, a plant derived
compound, against chikungunya virus (CHIKV) infection. Methods: Using flow cytometry and …

[PDF][PDF] The effects of ethanolic extract of Phaleria macrocarpa (Scheff.) Boerl leaf on macrophage phagocytic activity in diabetic rat model

IC Lestari, M Ghufron, S Herwiyanti… - Journal of thee …, 2018 - pdfs.semanticscholar.org
Diabetic patients suffer from inflammation and immune deficiency due to the decrease
macrophage activity that lead to vulnerable to infection. Phaleria macrocarpa (Scheff.) Boerl …

Natural Products as Immune System Modulators, and Against Infections of the Central Nervous System

A Parsaeimehr, HMN Iqbal, R Parra-Saldívar - The Microbiology of Central …, 2018 - Elsevier
Natural products have been used for traditional treatment of illnesses and diseases through
the ages, and they are still a unique source for discovery and developments of drugs. The …