Impact of Aging, Cytomegalovirus Infection, and Long-Term Treatment for Human Immunodeficiency Virus on CD8+ T-Cell Subsets

E Veel, L Westera, R Van Gent, L Bont, S Otto… - Frontiers in …, 2018 - frontiersin.org
Both healthy aging and human immunodeficiency virus (HIV) infection lead to a progressive
decline in naive CD8+ T-cell numbers and expansion of the CD8+ T-cell memory and …

Low IL-2 expressing t cells in thalassemia major patients: is it immune aging

B Pourgheysari, L Karimi, R Bagheri… - Indian Journal of …, 2018 - Springer
Several studies have demonstrated T cell alteration and some features of
immunosenescence in thalassemia major. Repeated alloimmunization converts naïve T …

Geroprotection in cancer prevention.

E Lasalvia-Prisco, C Dau, J Vázquez… - Advances in …, 2018 - europepmc.org
Clinical records from individuals followed for 5 years, 2000 to 2005, were reviewed. They
were distributed in 3 cohorts of ages ranging from 51 to 60, 61 to 70, and 71 to 80 years …

Investigating strategies to boost cutaneous varicella zoster virus-specific immune responses in ageing humans

NP Patel - 2018 - discovery.ucl.ac.uk
The age-related decline in the immune system, known as immunosenescence, predisposes
old individuals to increased mortality and morbidity from infectious diseases (such as …