Neurotrophic factors and neuroplasticity pathways in the pathophysiology and treatment of depression

MJF Levy, F Boulle, HW Steinbusch… - …, 2018 - Springer
Depression is a major health problem with a high prevalence and a heavy socioeconomic
burden in western societies. It is associated with atrophy and impaired functioning of cortico …

Epigenetic mechanisms of major depression: targeting neuronal plasticity

S Uchida, H Yamagata, T Seki… - Psychiatry and clinical …, 2018 - Wiley Online Library
Major depressive disorder is one of the most common mental illnesses as it affects more
than 350 million people globally. Major depressive disorder is etiologically complex and …

Psychedelics promote structural and functional neural plasticity

C Ly, AC Greb, LP Cameron, JM Wong, EV Barragan… - Cell reports, 2018 - cell.com
Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of
depression and related disorders. The ability to promote both structural and functional …

Fear of missing out: Testing relationships with negative affectivity, online social engagement, and problematic smartphone use

JD Elhai, JC Levine, AM Alghraibeh, AA Alafnan… - Computers in Human …, 2018 - Elsevier
In the present study, we empirically examined the “fear of missing out”(FOMO) construct and
its association with psychopathology-related and technology use measures. We carried out …

The role of stress in the pathogenesis and maintenance of obsessive-compulsive disorder

TG Adams, B Kelmendi, CA Brake, P Gruner… - Chronic …, 2018 - journals.sagepub.com
Individuals with obsessive-compulsive disorder often identify psychosocial stress as a factor
that exacerbates their symptoms, and many trace the onset of symptoms to a stressful period …

[HTML][HTML] Suggested biomarkers for major depressive disorder

Y Hacimusalar, E Eşel - Archives of Neuropsychiatry, 2018 - ncbi.nlm.nih.gov
Currently, the diagnosis of major depressive disorder (MDD) mainly relies on clinical
examination and subjective evaluation of depressive symptoms. There is no non-invasive …

Integrated metabolomics and proteomics analysis of hippocampus in a rat model of depression

Y Zhang, S Yuan, J Pu, L Yang, X Zhou, L Liu, X Jiang… - Neuroscience, 2018 - Elsevier
Major depressive disorder (MDD) is a prevalent and serious mental disorder with high rates
of suicide and disability. However, the underlying pathogenesis of MDD is complicated and …

[图书][B] The inflamed mind: a radical new approach to depression

E Bullmore - 2018 - books.google.com
As seen on" CBS This Morning" Worldwide, depression will be the single biggest cause of
disability in the next twenty years. But treatment for it has not changed much in the last three …

Erinacine A-Enriched Hericium erinaceus Mycelium Produces Antidepressant-Like Effects through Modulating BDNF/PI3K/Akt/GSK-3β Signaling in Mice

CH Chiu, CC Chyau, CC Chen, LY Lee… - International journal of …, 2018 - mdpi.com
Antidepressant-like effects of ethanolic extract of Hericium erinaceus (HE) mycelium
enriched in erinacine A on depressive mice challenged by repeated restraint stress (RS) …

Central role of glucocorticoid receptors in Alzheimer's disease and depression

G Canet, N Chevallier, C Zussy, C Desrumaux… - Frontiers in …, 2018 - frontiersin.org
Alzheimer's disease (AD) is the principal neurodegenerative pathology in the world
displaying negative impacts on both the health and social ability of patients and inducing …