Curcumin is a natural substance known for ages, exhibiting a multidirectional effect in cancer prevention and adjuvant cancer therapies. The great advantage of using …
AA Abu‐Hashem, MEA Zaki - Journal of Heterocyclic Chemistry, 2019 - Wiley Online Library
Isothiochromene [3, 4‐d] pyrimidine derivatives 2, 3, and 4a, b were synthesized from the reaction of 3‐amino‐1‐(pyridin‐4‐yl)‐5‐(pyridin‐4‐ylmethylene)‐5, 6, 7, 8‐tetrahydro‐1H …
Non-small cell lung cancer with ALK rearrangements can be targeted effectively with ALK inhibitors such as crizotinib. However, cancer progression typically occurs within a year as …
K Greish, H Nehoff, F Bahman, T Pritchard… - Journal of Drug …, 2019 - Taylor & Francis
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that differs in progression, recurrence, and prognosis from other forms of breast cancer. The …
We have previously shown that the curcumin derivative 3, 5-bis (3, 4, 5- trimethoxybenzylidene)-1-methylpiperidine-4-one (RL71), when encapsulated in styrene …
The naturally derived polyphenol curcumin has been investigated for prevention and treatment of many cancers over the past few decades. Accumulating evidence demonstrates …