Old trade, new tricks: insights into the spontaneous mutation process from the partnering of classical mutation accumulation experiments with high-throughput …

V Katju, U Bergthorsson - Genome Biology and Evolution, 2019 - academic.oup.com
Mutations spawn genetic variation which, in turn, fuels evolution. Hence, experimental
investigations into the rate and fitness effects of spontaneous mutations are central to the …

Spontaneous epimutations in plants

F Johannes, RJ Schmitz - New Phytologist, 2019 - Wiley Online Library
Contents Summary 1253 I. Introduction 1253 II. What is the rate and molecular spectrum of
spontaneous epimutations? 1254 III. Do spontaneous epimutations have phenotypic …

Population-level analysis reveals the widespread occurrence and phenotypic consequence of DNA methylation variation not tagged by genetic variation in maize

J Xu, G Chen, PJ Hermanson, Q Xu, C Sun, W Chen… - Genome biology, 2019 - Springer
Background DNA methylation can provide a source of heritable information that is
sometimes entirely uncoupled from genetic variation. However, the extent of this uncoupling …

Monitoring the interplay between transposable element families and DNA methylation in maize

JM Noshay, SN Anderson, P Zhou, L Ji, W Ricci… - PLoS …, 2019 - journals.plos.org
DNA methylation and epigenetic silencing play important roles in the regulation of
transposable elements (TEs) in many eukaryotic genomes. A majority of the maize genome …

Structure, stability and ecological significance of natural epigenetic variation: a large‐scale survey in Plantago lanceolata

B Gáspár, O Bossdorf, W Durka - New phytologist, 2019 - Wiley Online Library
Within‐species diversity is an important driver of ecological and evolutionary processes.
Recent research has found that plants can harbour significant epigenetic diversity, but its …

Identification of the expressome by machine learning on omics data

RC Sartor, J Noshay, NM Springer… - Proceedings of the …, 2019 - National Acad Sciences
Accurate annotation of plant genomes remains complex due to the presence of many
pseudogenes arising from whole-genome duplication-generated redundancy or the capture …

Transient stability of epigenetic population differentiation in a clonal invader

W Shi, X Chen, L Gao, CY Xu, X Ou… - Frontiers in plant …, 2019 - frontiersin.org
Epigenetic variation may play an important role in how plants cope with novel environments.
While significant epigenetic differences among plants from contrasting habitats have often …

Epigenetic mapping of the Arabidopsis metabolome reveals mediators of the epigenotype-phenotype map

R Kooke, L Morgado, F Becker, H van Eekelen… - Genome …, 2019 - genome.cshlp.org
Identifying the sources of natural variation underlying metabolic differences between plants
will enable a better understanding of plant metabolism and provide insights into the …

Contrasting DNA methylation responses of inbred fish lines to different rearing environments

WM Berbel-Filho, D Rodríguez-Barreto, N Berry… - Epigenetics, 2019 - Taylor & Francis
Epigenetic mechanisms generate plastic phenotypes that can become locally adapted
across environments. Disentangling genomic from epigenomic variation is challenging in …

Population epigenomics: advancing understanding of phenotypic plasticity, acclimation, adaptation and diseases

ERV Moler, A Abakir, M Eleftheriou, JS Johnson… - Population genomics …, 2019 - Springer
Advances in chromatin state mapping, high-throughput DNA sequencing, and bioinformatics
have revolutionized the study and interpretability of epigenomic variation. The increasing …