Microglia are the most abundant immune cells in the central nervous system (CNS), where
they interact with neurons and exhibit a wide array of functions in physiological and …

Mounting evidence suggests that neuroinflammation is not just a consequence but a vital
contributor to the development and progression of Parkinson's disease (PD). Microglia in …

Parkinson's disease (PD) is characterized by the accumulation of alpha-synuclein (α-syn)
inclusions, the major component of Lewy bodies. Extracellular α-syn aggregates act as a …

The role of neuroinflammation has been increasingly recognized in the field of
neurodegenerative diseases. Many studies focusing on the glial cells involved in the …

Neuroinflammation and oligodendroglial cytoplasmic α‐synuclein (α‐syn) inclusions (GCIs)
are important neuropathological characteristics of multiple system atrophy (MSA). GCIs are …

Parkinson's disease (PD) is the second most common neurodegenerative condition and
intracellular deposition of Lewy bodies in the substantia nigra (SN), which can cause …

The extracellular vesicles (EVs) represent a relatively new field of research in
neurodegenerative disease and they are thought to be one of the ways that …

Parkinson's disease (PD) is a progressive neurological disorder characterised by aberrant
accumulation of insoluble proteins, including alpha‐synuclein, and a loss of dopaminergic …

Abstract α-Synuclein (α-syn), a metabolite of neurons, induces glial activation and
neuroinflammation and participates in pathogenesis of neurodegenerative diseases. This …

Abstract Alpha-synuclein (α-Syn) is a soluble protein primarily expressed in presynaptic
terminals in the central nervous system (CNS). Aggregates of fibrillated α-Syn are the major …