Co‐shared genetics and possible risk gene pathway partially explain the comorbidity of schizophrenia, major depressive disorder, type 2 diabetes, and metabolic …

TT Postolache, L del Bosque‐Plata… - American Journal of …, 2019 - Wiley Online Library
Schizophrenia (SCZ) and major depressive disorder (MDD) in treatment‐naive patients are
associated with increased risk for type 2 diabetes (T2D) and metabolic syndrome (MetS) …

Distinguishing prodromal stage of bipolar disorder and early onset schizophrenia spectrum disorders during adolescence

HY Kafali, T Bildik, E Bora, Z Yuncu, HS Erermis - Psychiatry Research, 2019 - Elsevier
Prodromal symptoms of bipolar disorder (BD) and early onset schizophrenia spectrum
disorder (EOSSD) overlap. To date, there has been no study directly comparing the …

Reduced cortical thickness in subjects at clinical high risk for psychosis and clinical attributes

YB Kwak, M Kim, KIK Cho, J Lee… - Australian & New …, 2019 - journals.sagepub.com
Objectives: Although neuroanatomical abnormalities in subjects at clinical high risk for
psychosis have been considered a putative biomarker of psychosis, relevance of cortical …

Impact of distress related to attenuated psychotic symptoms in individuals at ultra high risk of psychosis: Findings from the Longitudinal Youth at Risk Study

G Rekhi, A Rapisarda, J Lee - Early Intervention in Psychiatry, 2019 - Wiley Online Library
Aim Recent studies have highlighted that attenuated psychotic symptoms (APS) are an
important source of distress in ultra high risk (UHR) individuals and that this distress is …

[HTML][HTML] Evaluation of the combined treatment approach “robin”(standardized manual and smartphone app) for adolescents at clinical high risk for psychosis

N Traber-Walker, M Gerstenberg, S Metzler… - Frontiers in …, 2019 - frontiersin.org
Introduction: The prevention of schizophrenia and other psychotic disorders has led
researchers to focus on early identification of individuals at clinical high risk (CHR) for …

Childhood temperament is associated with distress, anxiety and reduced quality of life in schizophrenia spectrum disorders

B Feola, K Armstrong, ND Woodward, S Heckers… - Psychiatry …, 2019 - Elsevier
Schizophrenia is conceptualized as a neurodevelopmental disorder and pre-morbid
differences in social function and cognition have been well-established. Less is known …

Two-year clinical and functional outcomes of an Asian cohort at ultra-high risk of psychosis

CT Chan, E Abdin, M Subramaniam, SA Tay… - Frontiers in …, 2019 - frontiersin.org
Background: To determine the 2-year clinical and functional outcomes of an Asian cohort at
ultra-high risk (UHR) of psychosis. Method: This was a longitudinal study with a follow-up …

Federated multi-site longitudinal study of at-risk mental state for psychosis in Japan

K Matsumoto, M Katsura, N Tsujino, S Nishiyama… - Schizophrenia …, 2019 - Elsevier
There has been recent accumulation of evidence and clinical guidance regarding the at-risk
mental state (ARMS) for psychosis. However, most studies have been observational cohort …

Staging of cognition in psychiatric illness

K Allott - Clinical Staging in Psychiatry: Making Diagnosis Work …, 2019 - cambridge.org
Disturbances in cognitive functioning, such as poor concentration and memory, slowed
speed of information processing, or difficulty organising one's thoughts are commonly …

The psychosis risk timeline: can we improve our preventive strategies? Part 2: adolescence and adulthood

K Romain, A Eriksson, R Onyon, M Kumar - BJPsych Advances, 2019 - cambridge.org
Current understanding of psychosis development is relevant to patients' clinical outcomes in
mental health services as a whole, given that psychotic symptoms can be a feature of many …