Malnutrition and sarcopenia

CC Sieber - Aging clinical and experimental research, 2019 - Springer
Risk for or established malnutrition is frequent in older adults, accompanied by functional
limitations, increased morbidity and mortality. Protein-energy malnutrition is often observed …

Inflamm‐aging: a new mechanism affecting premature ovarian insufficiency

Y Huang, C Hu, H Ye, R Luo, X Fu, X Li… - Journal of …, 2019 - Wiley Online Library
The normal function of ovaries, along with the secretion of sex hormones, is among the most
important endocrine factors that maintain the female sexual characteristics and promote …

[HTML][HTML] Cytokines for evaluation of chronic inflammatory status in ageing research: reliability and phenotypic characterisation

L Koelman, O Pivovarova-Ramich, AFH Pfeiffer… - Immunity & …, 2019 - Springer
Background There is a growing interest in the role of inflammageing for chronic disease
development. Cytokines are potent soluble immune mediators that can be used as target …

[HTML][HTML] The link between inflammaging and degenerative joint diseases

E Rezuș, A Cardoneanu, A Burlui, A Luca… - International journal of …, 2019 - mdpi.com
Aging is an inevitable process in the human body that is associated with a multitude of
systemic and localized changes. All these conditions have a common pathogenic …

[HTML][HTML] Oxidative-inflammatory stress in immune cells from adult mice with premature aging

A Garrido, J Cruces, N Ceprián, E Vara… - International journal of …, 2019 - mdpi.com
Oxidative and inflammatory stresses are closely related processes, which contribute to age-
associated impairments that affect the regulatory systems such as the immune system and …

Mendelian randomization analysis of C-reactive protein on colorectal cancer risk

X Wang, JY Dai, D Albanes, V Arndt… - International journal …, 2019 - academic.oup.com
Background Chronic inflammation is a risk factor for colorectal cancer (CRC). Circulating C-
reactive protein (CRP) is also moderately associated with CRC risk. However, observational …

[HTML][HTML] The association between frailty indicators and blood-based biomarkers in early-old community dwellers of Thailand

W Semmarath, M Seesen, S Yodkeeree… - International journal of …, 2019 - mdpi.com
Thailand has officially reached the status of an “aged society” and become the developing
country with the 2nd largest proportion of senior citizens in Southeast Asia. A cross-sectional …

[HTML][HTML] Classical monocytes from older adults maintain capacity for metabolic compensation during glucose deprivation and lipopolysaccharide stimulation

JR Yarbro, BD Pence - Mechanisms of ageing and development, 2019 - Elsevier
Inflammaging is the chronic low-grade inflammation that occurs with age that contributes to
the pathology of age-related diseases. Monocytes are innate immune cells that become …

Inflammaging phenotype in rhesus macaques is associated with a decline in epithelial barrier-protective functions and increased pro-inflammatory function in CD161 …

EM Walker, N Slisarenko, GL Gerrets, PJ Kissinger… - Geroscience, 2019 - Springer
The development of chronic inflammation, called inflammaging, contributes to the
pathogenesis of age-related diseases. Although it is known that both B and T lymphocyte …

[HTML][HTML] Growth differentiation factor 11 (GDF11) has pronounced effects on skin biology

J Idkowiak-Baldys, U Santhanam, SM Buchanan… - PLoS …, 2019 - journals.plos.org
Growth differentiation factor 11 (GDF11) belongs to the TGF-β superfamily of proteins and is
closely related to myostatin. Recent findings show that GDF11 has rejuvenating properties …