Organic semiconducting pro‐nanostimulants for near‐infrared photoactivatable cancer immunotherapy

J Li, D Cui, J Huang, S He, Z Yang… - Angewandte Chemie …, 2019 - Wiley Online Library
In this study, an organic semiconducting pro‐nanostimulant (OSPS) with a near‐infrared
(NIR) photoactivatable immunotherapeutic action for synergetic cancer therapy is presented …

Rational design of cancer nanomedicine for simultaneous stealth surface and enhanced cellular uptake

Q Jin, Y Deng, X Chen, J Ji - Acs Nano, 2019 - ACS Publications
Owing to the complex and still not fully understood physiological environment, the
development of traditional nanosized drug delivery systems is very challenging for precision …

Thermo-responsive triple-function nanotransporter for efficient chemo-photothermal therapy of multidrug-resistant bacterial infection

G Qing, X Zhao, N Gong, J Chen, X Li, Y Gan… - Nature …, 2019 - nature.com
New strategies with high antimicrobial efficacy against multidrug-resistant bacteria are
urgently desired. Herein, we describe a smart triple-functional nanostructure, namely …

Mesoporous polydopamine carrying manganese carbonyl responds to tumor microenvironment for multimodal imaging‐guided cancer therapy

D Wu, X Duan, Q Guan, J Liu, X Yang… - Advanced Functional …, 2019 - Wiley Online Library
Multifunctional nanodrugs integrating multiple therapeutic and imaging functions may find
tremendous biomedical applications. However, the development of a simple yet potent …

ROS-sensitive thioketal-linked polyphosphoester-doxorubicin conjugate for precise phototriggered locoregional chemotherapy

P Pei, C Sun, W Tao, J Li, X Yang, J Wang - Biomaterials, 2019 - Elsevier
Minimizing drug leakage at off-target sites and triggering sufficient drug release in tumor
tissue are major objectives for effective nanoparticle (NP)-based cancer therapy. The current …

Tumor microenvironment responsive shape-reversal self-targeting virus-inspired nanodrug for imaging-guided near-infrared-II photothermal chemotherapy

Y Li, J Lin, P Wang, Q Luo, H Lin, Y Zhang, Z Hou… - Acs Nano, 2019 - ACS Publications
Tumor microenvironment responsive multimodal synergistic theranostic strategies can
significantly improve the therapeutic efficacy while avoiding severe side effects. Inspired by …

Tumor microenvironment responsive drug‐dye‐peptide nanoassembly for enhanced tumor‐targeting, penetration, and photo‐chemo‐immunotherapy

J Peng, Q Yang, Y Xiao, K Shi, Q Liu… - Advanced Functional …, 2019 - Wiley Online Library
Nanomedicine constructed by therapeutics has unique and irreplaceable advantages in
biomedical applications, especially in drug delivery for cancer therapy. The strategy …

Programmed degradation of a hierarchical nanoparticle with redox and light responsivity for self-activated photo-chemical enhanced chemodynamic therapy

S Wang, L Yang, HY Cho, STD Chueng, H Zhang… - Biomaterials, 2019 - Elsevier
Chemodynamic therapy (CDT) has recently emerged as a promising treatment for cancer
due to the high specificity of CDT towards tumor microenvironment (TME). However, the low …

Intratumoral fate of functional nanoparticles in response to microenvironment factor: Implications on cancer diagnosis and therapy

J Peng, Q Yang, K Shi, Y Xiao, X Wei, Z Qian - Advanced Drug Delivery …, 2019 - Elsevier
The extraordinary growth and progression of tumor require enormous nutrient and energy.
Unregulated behaviors of cancer cell progressing and persistently change of tumor …

The future of peptides in cancer treatment

K Kurrikoff, D Aphkhazava, Ü Langel - Current Opinion in Pharmacology, 2019 - Elsevier
Highlights•Peptides from three distinct groups are important for cancer therapy and
diagnostics.•Anticancer peptides are most frequently mimics of natural proteins and …