Exosomes and microvesicles in normal physiology, pathophysiology, and renal diseases

A Ståhl, K Johansson, M Mossberg, R Kahn… - Pediatric …, 2019 - Springer
Extracellular vesicles are cell-derived membrane particles ranging from 30 to 5,000 nm in
size, including exosomes, microvesicles, and apoptotic bodies. They are released under …

Extracellular vesicles—connecting kingdoms

E Woith, G Fuhrmann, MF Melzig - International journal of molecular …, 2019 - mdpi.com
It is known that extracellular vesicles (EVs) are shed from cells of almost every type of cell or
organism, showing their ubiquity in all empires of life. EVs are defined as naturally released …

Bovine milk-derived exosomes enhance goblet cell activity and prevent the development of experimental necrotizing enterocolitis

B Li, A Hock, RY Wu, A Minich, SR Botts, C Lee… - PLoS one, 2019 - journals.plos.org
Necrotizing enterocolitis (NEC) is characterized by intestinal injury and impaired mucin
synthesis. We recently showed that breast milk exosomes from rodents promote intestinal …

Exosomes: isolation, analysis, and applications in cancer detection and therapy

H Bu, D He, X He, K Wang - Chembiochem, 2019 - Wiley Online Library
Exosomes are cell‐derived small extracellular vesicles that are naturally secreted by all
types of cells and widely distributed in various biofluids. They carry a variety of key bioactive …

Toward characterizing extracellular vesicles at a single-particle level

C Chiang, C Chen - Journal of biomedical science, 2019 - Springer
Extracellular vesicles (EVs) are cell-derived membrane-bound vesicles that serve a means
of cell-cell communication. Studying EVs at a single-particle level is important because EVs …

Breast milk-derived extracellular vesicles enriched in exosomes from mothers with type 1 diabetes contain aberrant levels of microRNAs

AH Mirza, S Kaur, LB Nielsen, J Størling… - Frontiers in …, 2019 - frontiersin.org
The breast milk plays a crucial role in shaping the initial intestinal microbiota and mucosal
immunity of the infant. Interestingly, breastfeeding has proven to be protective against the …

Extracellular vesicles in cardiovascular diseases: alternative biomarker sources, therapeutic agents, and drug delivery carriers

SY Chong, CK Lee, C Huang, YH Ou… - International journal of …, 2019 - mdpi.com
Cardiovascular diseases (CVD) represent the leading cause of morbidity and mortality
globally. The emerging role of extracellular vesicles (EVs) in intercellular communication …

Storage of extracellular vesicles in human milk, and microRNA profiles in human milk exosomes and infant formulas

A Leiferman, J Shu, B Upadhyaya, J Cui… - Journal of pediatric …, 2019 - journals.lww.com
The objectives of this study were to lay the methodological groundwork for field studies of
microRNA analysis in exosomes from small sample volumes of human milk, and assess …

A method for the isolation of exosomes from human and bovine milk

K Vaswani, MD Mitchell, OJ Holland… - Journal of Nutrition …, 2019 - Wiley Online Library
Scope. Milk provides a natural means of nutrient supply to infants. Exosomes are an
important component of milk that are not only being studied for their promise in translational …

Therapeutic potential of exosomes in rotator cuff tendon healing

DE Connor, JA Paulus, PJ Dabestani… - Journal of bone and …, 2019 - Springer
Rotator cuff tears are common musculoskeletal injuries that can cause significant pain and
disability. While the clinical results of rotator cuff repair can be good, failure of tendon …