MAPKAPK2: the master regulator of RNA-binding proteins modulates transcript stability and tumor progression

S Soni, P Anand, YS Padwad - Journal of Experimental & Clinical Cancer …, 2019 - Springer
The p38 mitogen-activated protein kinase (p38MAPK) pathway has been implicated in a
variety of pathological conditions including inflammation and metastasis. Post-transcriptional …

Lessons from studying the AU-rich elements in chronic inflammation and autoimmunity

N Lourou, M Gavriilidis, DL Kontoyiannis - Journal of Autoimmunity, 2019 - Elsevier
AU-rich elements (AREs) comprise one of the most widely studied families of regulatory
RNA structures met in RNAs engaged in complex immunological reactions. A multitude of …

[HTML][HTML] RNA-binding protein HuR regulates Rac1 nucleocytoplasmic shuttling through nucleophosmin in the intestinal epithelium

L Liu, L Xiao, HK Chung, MS Kwon, XX Li, N Wu… - Cellular and Molecular …, 2019 - Elsevier
Background & Aims The mammalian intestinal epithelium is a rapidly self-renewing tissue in
the body, and its homeostasis is tightly regulated via well-controlled mechanisms. The RNA …

HuR controls apoptosis and activation response without effects on cytokine 3'UTRs

FV Karginov - RNA biology, 2019 - Taylor & Francis
ABSTRACT RNA binding proteins regulate gene expression through several post-
transcriptional mechanisms. The broadly expressed HuR/ELAVL1 is important for proper …

[PDF][PDF] A study of the function of hnRNP A3 in the myeloid lineage and innate immunity

A Ferentinos, BA Fleming - 2019 - pergamos.lib.uoa.gr
The innate immune response against pathogens involves the activation of pro-inflammatory
processes that need to be resolved once the threat is removed. The successful regulation of …