The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Gut microbiota in colorectal cancer: mechanisms of action and clinical applications

SH Wong, J Yu - Nature reviews Gastroenterology & hepatology, 2019 - nature.com
Colorectal cancer (CRC) accounts for about 10% of all new cancer cases globally. Located
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …

Probiotics and prebiotics in intestinal health and disease: from biology to the clinic

ME Sanders, DJ Merenstein, G Reid… - Nature reviews …, 2019 - nature.com
Probiotics and prebiotics are microbiota-management tools for improving host health. They
target gastrointestinal effects via the gut, although direct application to other sites such as …

[HTML][HTML] Gut microbiome: profound implications for diet and disease

RD Hills, BA Pontefract, HR Mishcon, CA Black… - Nutrients, 2019 - mdpi.com
The gut microbiome plays an important role in human health and influences the
development of chronic diseases ranging from metabolic disease to gastrointestinal …

Alteration of gut microbiota in inflammatory bowel disease (IBD): cause or consequence? IBD treatment targeting the gut microbiome

I Khan, N Ullah, L Zha, Y Bai, A Khan, T Zhao, T Che… - Pathogens, 2019 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic complex inflammatory gut pathological
condition, examples of which include Crohn's disease (CD) and ulcerative colitis (UC) …

Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer

J Wirbel, PT Pyl, E Kartal, K Zych, A Kashani… - Nature medicine, 2019 - nature.com
Association studies have linked microbiome alterations with many human diseases.
However, they have not always reported consistent results, thereby necessitating cross …

Gut microbial metabolites in obesity, NAFLD and T2DM

EE Canfora, RCR Meex, K Venema… - Nature Reviews …, 2019 - nature.com
Evidence is accumulating that the gut microbiome is involved in the aetiology of obesity and
obesity-related complications such as nonalcoholic fatty liver disease (NAFLD), insulin …

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

T Tanoue, S Morita, DR Plichta, AN Skelly, W Suda… - Nature, 2019 - nature.com
There is a growing appreciation for the importance of the gut microbiota as a therapeutic
target in various diseases. However, there are only a handful of known commensal strains …

[HTML][HTML] Microbes, metabolites, and the gut–lung axis

AT Dang, BJ Marsland - Mucosal immunology, 2019 - Elsevier
The microbiota plays an essential role in the education, development, and function of the
immune system, both locally and systemically. Emerging experimental and epidemiological …

An insight into gut microbiota and its functionalities

A Adak, MR Khan - Cellular and Molecular Life Sciences, 2019 - Springer
Gut microbiota has evolved along with their hosts and is an integral part of the human body.
Microbiota acquired at birth develops in parallel as the host develops and maintains its …