Cannabidiol adverse effects and toxicity

MA Huestis, R Solimini, S Pichini… - Current …, 2019 - ingentaconnect.com
Background: Currently, there is a great interest in the potential medical use of cannabidiol
(CBD), a non-intoxicating cannabinoid. Productive pharmacological research on CBD …

Cannabidiol (CBD) use in psychiatric disorders: A systematic review

S Bonaccorso, A Ricciardi, C Zangani, S Chiappini… - Neurotoxicology, 2019 - Elsevier
Abstract Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are the most represented
phytocannabinoids in Cannabis sativa plants. However, CBD may present with a different …

Cannabidiol for the reduction of cue-induced craving and anxiety in drug-abstinent individuals with heroin use disorder: a double-blind randomized placebo-controlled …

YL Hurd, S Spriggs, J Alishayev… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Despite the staggering consequences of the opioid epidemic, limited nonopioid
medication options have been developed to treat this medical and public health crisis. This …

[HTML][HTML] The neuropsychopharmacology of cannabis: A review of human imaging studies

MAP Bloomfield, C Hindocha, SF Green… - Pharmacology & …, 2019 - Elsevier
The laws governing cannabis are evolving worldwide and associated with changing
patterns of use. The main psychoactive drug in cannabis is Δ 9-tetrahydrocannabinol (THC) …

[HTML][HTML] The endocannabinoid system and cannabidiol's promise for the treatment of substance use disorder

Y Chye, E Christensen, N Solowij, M Yücel - Frontiers in psychiatry, 2019 - frontiersin.org
Substance use disorder is characterized by repeated use of a substance, leading to
clinically significant distress, making it a serious public health concern. The …

[HTML][HTML] Cannabinoid regulation of fear and anxiety: an update

EP Papagianni, CW Stevenson - Current psychiatry reports, 2019 - Springer
Abstract Purpose of Review Anxiety-and trauma-related disorders are prevalent and
debilitating mental illnesses associated with a significant socioeconomic burden. Current …

A marijuana-drug interaction primer: precipitants, pharmacology, and pharmacokinetics

EJ Cox, N Maharao, G Patilea-Vrana… - Pharmacology & …, 2019 - Elsevier
Abstract In the United States, the evolving landscape of state-legal marijuana use for
recreational and/or medical purposes has given rise to flourishing markets for marijuana and …

Modulatory effects of cannabinoids on brain neurotransmission

K Cohen, A Weizman… - European Journal of …, 2019 - Wiley Online Library
Recreational and chronic cannabis use has been associated with a range of acute and
chronic effects including; anti‐nociceptive actions, anxiety, depression, psychotic symptoms …

Cannabidiol does not display drug abuse potential in mice behavior

A Viudez-Martínez, MS García-Gutiérrez… - Acta Pharmacologica …, 2019 - nature.com
Recent evidence suggests that cannabidiol (CBD) may be useful for the treatment of
different neuropsychiatric disorders. However, some controversy regarding its profile as a …

Cannabis use behaviors and prevalence of anxiety and depressive symptoms in a cohort of Canadian medicinal cannabis users

J Turna, W Simpson, B Patterson, P Lucas… - Journal of psychiatric …, 2019 - Elsevier
Cannabis is commonly used recreationally for its euphoric and relaxing effects, while its
medical use is permitted in several jurisdictions. With only low-quality evidence suggesting …