The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis
Background Ageing is one of the principal risk factors for many chronic diseases. However,
there is considerable between-person variation in the rate of ageing and individual …
there is considerable between-person variation in the rate of ageing and individual …
Measuring aging and identifying aging phenotypes in cancer survivors
JL Guida, TA Ahles, D Belsky, J Campisi… - JNCI: Journal of the …, 2019 - academic.oup.com
Observational data have shown that some cancer survivors develop chronic conditions like
frailty, sarcopenia, cardiac dysfunction, and mild cognitive impairment earlier and/or at a …
frailty, sarcopenia, cardiac dysfunction, and mild cognitive impairment earlier and/or at a …
Epigenetic clock: just a convenient marker or an active driver of aging?
VV Ashapkin, LI Kutueva, BF Vanyushin - … studies in aging and anti-aging …, 2019 - Springer
A global DNA hypomethylation and local changes in the methylation levels of specific DNA
loci occur during aging in mammals. Global hypomethylation mainly affects highly …
loci occur during aging in mammals. Global hypomethylation mainly affects highly …
Methylation-based biological age and breast cancer risk
Background Age is one of the strongest predictors of cancer, chronic disease, and mortality,
but biological responses to aging differ among people. Epigenetic DNA modifications have …
but biological responses to aging differ among people. Epigenetic DNA modifications have …
Posttraumatic psychopathology and the pace of the epigenetic clock: a longitudinal investigation
BackgroundPosttraumatic stress disorder (PTSD) and stress/trauma exposure are cross-
sectionally associated with advanced DNA methylation age relative to chronological age …
sectionally associated with advanced DNA methylation age relative to chronological age …
Missing value estimation methods for DNA methylation data
Motivation DNA methylation is a stable epigenetic mark with major implications in both
physiological (development, aging) and pathological conditions (cancers and numerous …
physiological (development, aging) and pathological conditions (cancers and numerous …
Impact of a diet and activity health promotion intervention on regional patterns of DNA methylation
Background Studies demonstrate the impact of diet and physical activity on epigenetic
biomarkers, specifically DNA methylation. However, no intervention studies have examined …
biomarkers, specifically DNA methylation. However, no intervention studies have examined …
Shift work, DNA methylation and epigenetic age
Background Shift work has been associated with increased risk of age-related morbidity and
mortality. Biological age, estimated using DNA methylation (DNAm), may quantify the …
mortality. Biological age, estimated using DNA methylation (DNAm), may quantify the …
DNA methylation correlates of PTSD: Recent findings and technical challenges
There is increasing evidence that epigenetic factors play a critical role in posttraumatic
stress disorder (PTSD), by mediating the impact of environmental exposures to trauma on …
stress disorder (PTSD), by mediating the impact of environmental exposures to trauma on …
A longitudinal, epigenome-wide study of DNA methylation in anorexia nervosa: results in actively ill, partially weight-restored, long-term remitted and non-eating …
Background: This study explored state-related tendencies in DNA methylation in people with
anorexia nervosa. Methods: We measured genome-wide DNA methylation in 75 women …
anorexia nervosa. Methods: We measured genome-wide DNA methylation in 75 women …