Bioprinting vasculature: materials, cells and emergent techniques

C Tomasina, T Bodet, C Mota, L Moroni… - Materials, 2019 - mdpi.com
Despite the great advances that the tissue engineering field has experienced over the last
two decades, the amount of in vitro engineered tissues that have reached a stage of clinical …

Engineering blood vessels and vascularized tissues: technology trends and potential clinical applications

P Chandra, A Atala - Clinical Science, 2019 - portlandpress.com
Vascular tissue engineering has the potential to make a significant impact on the treatment
of a wide variety of medical conditions, including providing in vitro generated vascularized …

Layer-specific cell differentiation in bi-layered vascular grafts under flow perfusion

I Pennings, EE van Haaften, T Jungst, JA Bulsink… - …, 2019 - iopscience.iop.org
Bioengineered grafts have the potential to overcome the limitations of autologous and non-
resorbable synthetic vessels as vascular substitutes. However, one of the challenges in …

Nrf-2 signaling inhibits intracranial aneurysm formation and progression by modulating vascular smooth muscle cell phenotype and function

Y Shi, S Li, Y Song, P Liu, Z Yang, Y Liu… - Journal of …, 2019 - Springer
Background Oxidative stress and vascular smooth muscle cell (VSMC) phenotypic
modulation influence intracranial aneurysm (IA) formation and progression. Oxidative stress …

Evaluation of a simple off-the-shelf bi-layered vascular scaffold based on poly (L-lactide-co-ε-caprolactone)/silk fibroin in vitro and in vivo

D Jin, J Hu, D Xia, A Liu, H Kuang, J Du… - International Journal of …, 2019 - Taylor & Francis
Purpose: In the field of small-caliber vascular scaffold research, excellent vascular
remodeling is the key to ensuring anticoagulant function. We prepared an off-the-shelf bi …

[HTML][HTML] miR-149-5p inhibits vascular smooth muscle cells proliferation, invasion, and migration by targeting histone deacetylase 4 (HDAC4)

B Zhang, Y Dong, M Liu, L Yang… - Medical Science Monitor …, 2019 - ncbi.nlm.nih.gov
miR-149-5p Inhibits Vascular Smooth Muscle Cells Proliferation, Invasion, and Migration by
Targeting Histone Deacetylase 4 (HDAC4) - PMC Back to Top Skip to main content NIH NLM …

[HTML][HTML] Atherosclerosis-associated differentially methylated regions can reflect the disease phenotype and are often at enhancers

M Lacey, C Baribault, KC Ehrlich, M Ehrlich - Atherosclerosis, 2019 - Elsevier
Background and aims Atherosclerosis is a widespread and complicated disease involving
phenotypic modulation and transdifferentiation of vascular smooth muscle cells (SMCs), the …

Liraglutide inhibits endothelial-to-mesenchymal transition and attenuates neointima formation after endovascular injury in streptozotocin-induced diabetic mice

TH Tsai, CH Lee, CI Cheng, YN Fang, SY Chung… - Cells, 2019 - mdpi.com
Hyperglycaemia causes endothelial dysfunction, which is the initial process in the
development of diabetic vascular complications. Upon injury, endothelial cells undergo an …

Modulating smooth muscle cell response by the release of TGFβ2 from tubular scaffolds for vascular tissue engineering

DC Ardila, E Tamimi, T Doetschman… - Journal of Controlled …, 2019 - Elsevier
Tissue engineering has gained considerable attention in the development of small diameter
tissue engineered vascular grafts (TEVGs) for treating coronary heart disease. A properly …

Endothelial/epithelial mesenchymal transition in ascending aortas of patients with bicuspid aortic valve

S Maleki, FA Poujade, O Bergman, JR Gådin… - Frontiers in …, 2019 - frontiersin.org
Thoracic aortic aneurysm (TAA) is the progressive enlargement of the aorta due to
destructive changes in the connective tissue of the aortic wall. Aneurysm development is …