[HTML][HTML] MicroRNA amplification and detection technologies: opportunities and challenges for point of care diagnostics

VP Dave, TA Ngo, AK Pernestig, D Tilevik, K Kant… - Laboratory …, 2019 - Elsevier
The volume of point of care (POC) testing continues to grow steadily due to the increased
availability of easy-to-use devices, thus making it possible to deliver less costly care closer …

2D materials in development of electrochemical point-of-care cancer screening devices

M Mohammadniaei, HV Nguyen, MV Tieu, MH Lee - Micromachines, 2019 - mdpi.com
Effective cancer treatment requires early detection and monitoring the development
progress in a simple and affordable manner. Point-of care (POC) screening can provide a …

Serum levels of miR-29, miR-122, miR-155 and miR-192 are elevated in patients with cholangiocarcinoma

SH Loosen, G Lurje, G Wiltberger, M Vucur, A Koch… - PLoS …, 2019 - journals.plos.org
Objectives Cholangiocarcinoma (CCA) represents the second most common primary
hepatic malignancy. Despite tremendous research activities, the prognosis for the majority of …

FBXL19-AS1 exerts oncogenic function by sponging miR-431-5p to regulate RAF1 expression in lung cancer

Q Jiang, L Cheng, D Ma, Y Zhao - Bioscience reports, 2019 - portlandpress.com
Lung cancer is the leading cause of cancer-related mortality worldwide, characterized by
uncontrolled proliferation and metastasis of lung cancer cells. Tumor angiogenesis plays a …

LncRNA SNHG16 sponges miR-98-5p to regulate cellular processes in osteosarcoma

S Liao, S Xing, Y Ma - Cancer chemotherapy and pharmacology, 2019 - Springer
Background As has been illustrated that long noncoding RNAs (lncRNAs) and microRNAs
(miRNAs) are potential regulators in the occurrence and progression of human cancers …

LncRNA HOXA-AS3 Sponges miR-29c to Facilitate Cell Proliferation, Metastasis, and EMT Process and Activate the MEK/ERK Signaling Pathway in Hepatocellular …

Y Tong, M Wang, Y Dai, D Bao, J Zhang… - Human Gene Therapy …, 2019 - liebertpub.com
Hepatocellular carcinoma (HCC) is a prevalent malignant tumor with high morbidity and
mortality across the world. Recent findings have suggested that long noncoding (lnc) RNA …

LINC01006 promotes cell proliferation and metastasis in pancreatic cancer via miR-2682-5p/HOXB8 axis

L Zhang, Y Wang, L Zhang, G You, C Li, B Meng… - Cancer cell …, 2019 - Springer
Background Pancreatic cancer (PC) is one of the deadliest cancers about the digestive
system. Recent researches have validated that long non-coding RNAs (lncRNAs) play vital …

Exosomal miRNAs as Biomarkers of Cancer: a Meta-Analysis.

B Yang, WY Xiong, HJ Hou, Q Xu, XL Cai… - Clinical …, 2019 - search.ebscohost.com
Background: Tumor-derived exosomal miRNAs secreted by cancer cells play significant
roles in the pathological processes of cancer, but no systematic meta-analysis has focused …

Interplay between the androgen receptor signaling axis and microRNAs in prostate cancer

RC Fernandes, TE Hickey, WD Tilley… - Endocrine-related …, 2019 - erc.bioscientifica.com
The androgen receptor (AR) is a ligand activated transcription factor that drives prostate
cancer. Since therapies that target the AR are the mainstay treatment for men with metastatic …

MiR-193a-3p inhibits pancreatic ductal adenocarcinoma cell proliferation by targeting CCND1

ZM Chen, Q Yu, G Chen, RX Tang, DZ Luo… - Cancer management …, 2019 - Taylor & Francis
Background: MicroRNAs (miRNAs) could modulate gene expression at the
posttranscriptional level by promoting mRNA degradation or blocking mRNA translation …