Interplay between small and long non‐coding RNA s in cutaneous melanoma: a complex jigsaw puzzle with missing pieces

M Riefolo, E Porcellini, E Dika, E Broseghini… - Molecular …, 2019 - Wiley Online Library
The incidence of cutaneous melanoma (CM) has increased in the past few decades. The
biology of melanoma is characterized by a complex interaction between genetic …

Development of a database on key characteristics of human carcinogens

M Al-Zoughool, M Bird, J Rice, RA Baan… - Journal of Toxicology …, 2019 - Taylor & Francis
ABSTRACT A database on mechanistic characteristics of human carcinogenic agents was
developed by collecting mechanistic information on agents identified as human carcinogens …

nc886, a non-coding RNA, inhibits UVB-induced MMP-9 and COX-2 expression via the PKR pathway in human keratinocytes

KS Lee, S Shin, E Cho, WK Im, SH Jeon, Y Kim… - Biochemical and …, 2019 - Elsevier
Abstract nc886, a long non-coding RNA (ncRNA) of 101 nucleotides in length, is known as a
vault RNA or microRNA precursor. Despite the recent discovery that ncRNAs in the nucleus …

Ionizing radiation-induced growth in soft agar is associated with miR-21 upregulation in wild-type and DNA double strand break repair deficient cells

S Tang, B Liu, M Liu, Z Li, J Liu, H Wang, J Wang… - DNA repair, 2019 - Elsevier
DNA double strand breaks (DSBs) are a severe threat to genome integrity and a potential
cause of tumorigenesis, which is a multi-stage process and involves many factors including …

[HTML][HTML] 皮肤角质形成细胞光老化模型的构建及老化机制的初步研究

刘川, 黄欣, 王萍, 潘芸, 曹迪, 刘依依, 陈爱军 - 2019 - aammt.tmmu.edu.cn
目的建立有效的皮肤光老化HaCaT 细胞模型, 初步探索可能涉及的老化相关信号转导途径.
方法以30 mJ/cm 2 中波紫外线(ultraviolet B, UVB) 辐照HaCaT 细胞, 采用CCK-8 …

Protective Effects of 2′, 3′-Dihydroxy-4′, 6′-dimethoxychalcone Derived from Green Perilla Leaves against UV Radiation-Induced Cell Injury in Human Cultured …

Y Takada-Takatori, Y Tomii, S Takemasa… - Biological and …, 2019 - jstage.jst.go.jp
Skin exposure to UV rays causes the production of reactive oxygen species (ROS), and it is
a major risk factor for various skin disorders and diseases. In particular, exposure to UV-A is …

Dose and time effects of solar-simulated ultraviolet radiation on the in vivo human skin transcriptome

M Bustamante Pineda… - Br J Dermatol. 2020; …, 2019 - repositori.upf.edu
BACKGROUND: Terrestrial ultraviolet (UV) radiation causes erythema, oxidative stress,
DNA mutations and skin cancer. Skin can adapt to these adverse effects by DNA repair …